Extracorporeal Organ Support for Burn-Injured Patients

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-03-25 DOI:10.3390/ebj5020006

Garrett W. Britton, Amanda R. Keith, Barret J. Halgas, Joshua M. Boster, Nicholas S. Niazi, Kevin K. Chung, L. Cancio

引用次数: 0

Abstract

As mortality relating to severe acute burn injury improves, patients are surviving longer into the critical care phase, which is commonly complicated by multisystem organ failure. Extracorporeal organ support (ECOS) represents a set of potential therapeutic technologies for managing patients with organ-specific complications. This article provides a comprehensive review of the existing literature, focusing on the use of continuous kidney replacement therapy, extracorporeal membrane oxygenation, extracorporeal carbon dioxide removal, and extracorporeal blood purification. Though promising, many of these technologies are in the early phases of implementation and are restricted to well-resourced medical systems, limiting their use in large scale casualty and austere scenarios.

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为烧伤患者提供体外器官支持

随着严重急性烧伤死亡率的降低，患者进入重症监护阶段的存活时间越来越长，而重症监护阶段通常会并发多系统器官衰竭。体外器官支持（ECOS）代表了一套潜在的治疗技术，可用于管理出现器官特异性并发症的患者。本文全面回顾了现有文献，重点介绍了持续肾脏替代疗法、体外膜氧合、体外二氧化碳清除和体外血液净化的应用。尽管这些技术前景广阔，但其中许多仍处于早期实施阶段，而且仅限于资源充足的医疗系统，限制了它们在大规模伤亡和艰苦环境下的使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.