Investigation of factors affecting reintervention after type A aortic dissection

Mustafa Can Kaplan, Ersin Kadiroğulları, S. Guler, B. Timur, Kemal Kutanis, Emre Yaşar, Batuhan Yazici, Unal Aydin
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Abstract

Aim: Our study aims to share the reintervention results of patients who were operated with the diagnosis of Type A aortic dissection and to examine the factors that cause reintervention. Material and Methods: In our single-center retrospective study, 244 patients who underwent surgery due to Type A aortic dissection between November 2010 and June 2021 were included. Results for patients who underwent reintervention and factors which caused reintervention were compared with demographic data, preoperative, intraoperative and postoperative variables. Results: A total of 142 patients were included in the study and 15.5% of them underwent reintervention. Reoperation was performed in 8 (36.4%) of 22 patients who underwent reintervention, while thoracic aortic endovascular repair was performed in 14 (63.6%) patients. Post-procedure mortality was observed in 5 (22.7%) of the patients who underwent reintervention. The mean age of the patients who underwent reintervention was 46.6±13.2 and there was a statistically significant (p<0.05) difference between the groups (p: 0.026). Results that were significant for reintervention were multivariate analysis with cox regression and it was shown that the persistence of postoperative hypertension with total arch surgery was a risk factor for reintervention (p: 0.03, p: 0.008). Conclusion: Type A aortic dissection is not considered to be completely cured after the first operation. It is necessary to evaluate the patients in terms of reintervention with close follow-up. We propose that patients who underwent total arch surgery during the first operation and hypertension in the postoperative period are risk factors for reintervention.
影响 A 型主动脉夹层术后再介入的因素调查
目的:我们的研究旨在分享诊断为 A 型主动脉夹层的手术患者的再介入结果,并探讨导致再介入的因素。材料与方法:在我们的单中心回顾性研究中,纳入了 2010 年 11 月至 2021 年 6 月期间因 A 型主动脉夹层接受手术的 244 例患者。将接受再介入手术患者的结果和导致再介入的因素与人口统计学数据、术前、术中和术后变量进行比较。结果:研究共纳入了 142 名患者,其中 15.5% 的患者接受了再介入手术。在接受再介入治疗的 22 名患者中,有 8 人(36.4%)接受了再手术,14 人(63.6%)接受了胸主动脉血管内修复术。在接受再介入治疗的患者中,有 5 人(22.7%)出现术后死亡。接受再介入治疗的患者平均年龄为(46.6±13.2)岁,组间差异有统计学意义(P<0.05)(P:0.026)。使用 cox 回归进行多变量分析的结果显示,全弓手术后持续高血压是再次干预的风险因素(p:0.03,p:0.008)。结论A 型主动脉夹层在首次手术后并不能被视为完全治愈。有必要通过密切随访来评估患者的再介入情况。我们认为,在首次手术中接受全弓手术的患者和术后高血压是再次干预的风险因素。
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