Plant pangenomics, current practice and future direction

Haifei Hu , Jian Wang , Shuai Nie , Junliang Zhao , Jacqueline Batley , David Edwards
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Abstract

A pangenome encompasses the complete genetic diversity of a species, by assembling a range of representative individuals from various populations. This review describes the advances in plant pangenomics, tracing its evolution since the initial plant genome sequencing in 2000, and provides comprehensive best-practice advice to build a linear or graphical pangenome, delineating the strengths and limitations of different pangenome construction methods. The review also examines the challenges in pangenome data visualisation, the challenges of graph-based pangenomes and their utility in investigating the potential function of genome variation. Furthermore, we examine the application of pangenomes in plant breeding, including the identification of genetic diversity for crop improvement, and the integration of multi-omics data into pangenome databases to advance plant breeding.

植物泛基因组学、当前实践和未来方向
庞基因组通过汇集来自不同种群的一系列代表性个体,囊括了一个物种完整的遗传多样性。本综述介绍了植物泛基因组学的进展,追溯了自 2000 年首次植物基因组测序以来植物泛基因组学的演变,并为构建线性或图形泛基因组提供了全面的最佳实践建议,划分了不同泛基因组构建方法的优势和局限性。综述还探讨了庞基因组数据可视化的挑战、基于图形的庞基因组的挑战及其在研究基因组变异潜在功能方面的作用。此外,我们还探讨了庞基因组在植物育种中的应用,包括鉴定用于作物改良的遗传多样性,以及将多组学数据整合到庞基因组数据库中以促进植物育种。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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