Evolution of epilepsy surgery in childhood: the neurologist's point of view

IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY
Jean Aicardi
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引用次数: 0

Abstract

Surgical treatment of epilepsy in children has been slow to develop because of uncertainties regarding the prognosis of early epilepsies, difficulties in the diagnosis of causal lesions, the frequency of severe, extensive brain damage, and technical problems. Surgery for epilepsy in infants and children raises problems quite different from those in adults. This applies especially to severe infantile epilepsies for which the aim of treatment may be more to facilitate neurodevelopment than to control the seizures. In addition, intractability cannot be defined in the same terms at different ages, the time scale being usually much shorter in young children and the operations required often extensive. The results of surgery in childhood are comparable to those in adults. However, indications for surgery and assessment of its results in catastrophic epilepsies of infants requires different rules to those that apply to adults and older children.
儿童癫痫手术的演变:神经学家的观点
由于对早期癫痫预后的不确定性、病因诊断的困难、严重和广泛脑损伤的发生率以及技术问题,儿童癫痫的外科治疗一直发展缓慢。婴幼儿癫痫的手术治疗所面临的问题与成人截然不同。这尤其适用于严重的婴幼儿癫痫,因为治疗的目的可能更多是促进神经发育,而不是控制癫痫发作。此外,难治性在不同年龄段的定义也不尽相同,幼儿的治疗时间通常要短得多,所需的手术通常也很广泛。儿童期手术的效果与成人相当。然而,婴儿灾难性癫痫的手术指征和手术效果评估需要与成人和较大儿童不同的规则。
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来源期刊
Epileptic Disorders
Epileptic Disorders 医学-临床神经学
CiteScore
4.10
自引率
8.70%
发文量
138
审稿时长
6-12 weeks
期刊介绍: Epileptic Disorders is the leading forum where all experts and medical studentswho wish to improve their understanding of epilepsy and related disorders can share practical experiences surrounding diagnosis and care, natural history, and management of seizures. Epileptic Disorders is the official E-journal of the International League Against Epilepsy for educational communication. As the journal celebrates its 20th anniversary, it will now be available only as an online version. Its mission is to create educational links between epileptologists and other health professionals in clinical practice and scientists or physicians in research-based institutions. This change is accompanied by an increase in the number of issues per year, from 4 to 6, to ensure regular diffusion of recently published material (high quality Review and Seminar in Epileptology papers; Original Research articles or Case reports of educational value; MultiMedia Teaching Material), to serve the global medical community that cares for those affected by epilepsy.
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