Complement: you gutsy thing!

IF 13.1 1区医学 Q1 IMMUNOLOGY

Trends in Immunology Pub Date : 2024-04-01 Epub Date: 2024-03-26 DOI:10.1016/j.it.2024.03.003

Claudia Kemper

引用次数: 0

Abstract

Complement, traditionally perceived as a liver-derived and plasma-operative guardian against bloodborne pathogens, is increasingly recognized as a local and central player in tissue immunity. Two recent studies, by Xu et al. and Wu et al., validate this concept in the mouse gut, where extrahepatic, intestine-produced, and/or operative C3 protects against enteric infections.

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补充：你真有胆量！

补体，传统上被认为是肝脏来源和血浆操作的抵御血源性病原体的守护者，但人们越来越认识到它是组织免疫的局部和核心角色。最近，Xu 等人和 Wu 等人的两项研究在小鼠肠道中验证了这一概念，在肠道中，肝外、肠道产生的和/或操作性 C3 可抵御肠道感染。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in Immunology 医学-免疫学

CiteScore

25.10

自引率

0.60%

发文量

130

审稿时长

6-12 weeks

期刊介绍： Trends in Immunology serves as a vital platform for tracking advancements across various areas of immunology, offering concise reviews and hypothesis-driven viewpoints in each issue. With additional sections providing comprehensive coverage, the journal offers a holistic view of immunology. This broad perspective makes it an invaluable resource for researchers, educators, and students, facilitating the connection between basic and clinical immunology. Recognized as one of the top monthly review journals in its field, Trends in Immunology is highly regarded by the scientific community.