Ancestral β-globin gene haplotypes modify β-thalassemia severity in a mouse model.

IF 7.4 1区医学 Q1 HEMATOLOGY

Blood advances Pub Date : 2024-12-10 DOI:10.1182/bloodadvances.2024012681

Christophe Lechauve, Julia Keith, Michael W Dudley, Alfonso G Fernandez, Eugene Khandros, Kalin Mayberry, Thiyagaraj Mayuranathan, Lance Palmer, Xiaohui Qiu, Heather Sheppard, Rahul Telange, Hans-Martin Herz, Mitchell J Weiss

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祖先β-球蛋白基因单倍型可改变小鼠模型中β-地中海贫血症的严重程度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Blood advances Medicine-Hematology

CiteScore

12.70

自引率

2.70%

发文量

840

期刊介绍： Blood Advances, a semimonthly medical journal published by the American Society of Hematology, marks the first addition to the Blood family in 70 years. This peer-reviewed, online-only, open-access journal was launched under the leadership of founding editor-in-chief Robert Negrin, MD, from Stanford University Medical Center in Stanford, CA, with its inaugural issue released on November 29, 2016. Blood Advances serves as an international platform for original articles detailing basic laboratory, translational, and clinical investigations in hematology. The journal comprehensively covers all aspects of hematology, including disorders of leukocytes (both benign and malignant), erythrocytes, platelets, hemostatic mechanisms, vascular biology, immunology, and hematologic oncology. Each article undergoes a rigorous peer-review process, with selection based on the originality of the findings, the high quality of the work presented, and the clarity of the presentation.