Chemical composition and antimicrobial properties of Morchella crassipes from Kashmir Valley, India

IF 1.4 4区生物学 Q4 MYCOLOGY

International journal of medicinal mushrooms Pub Date : 2024-03-01 DOI:10.1615/intjmedmushrooms.2024053250

MEHRAJUDDIN TALIE, John Mohd War, Anees Un Nisa, Asif Hamid Dar, Abdul Hamid Wani, Mohd Yaqub Bhat

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引用次数: 0

Abstract

In the current era, wild macrofungi are being focused for developing and discovering novel bioactive compounds for the management of agricultural, horticultural, and other infectious diseases. In that view, current research work was designed to evaluate the biochemical composition and medicinal properties of Morchella crassipes mushroom. The phytochemical screening of aqueous extract exposed the incidence of glycosides, free amino acids and proteins, alkaloids, carbs, flavonoids, terpenoids, phenolic compounds and tannins, except volatile oils, resins, steroids, and anthraquinones. However, hexane extract exhibited the occurrence of glycosides, alkaloids, volatile oils, steroids and terpenoids while as all other phytochemicals were not detected. The gas chromatography mass spectrometry profiling has disclosed the identification of three predominant naturally occurring bioactive volatile monoterpenoids, namely Neral, Citral, and Epoxy-linalool oxide with well-known biological activities. The methanolic extract resulted in strong antifungal efficacy against the tested fungal strains such as Penicillium chrysogenum (20.33±0.57 mm) followed by Pythium ultimum (15.33±0.76 mm) and Aspergillus niger (12.50±0.50 mm) at highest concentrations. Likewise, marked antibacterial effects were reported in case of Staphylococcus aureus (15.16±0.76 mm), followed by Salmonella gallinarum (14.33±0.57 mm) and Escherichia coli (13.66±0.57 mm), respectively. This data may offer baseline information regarding the bioactive metabolites and opening new ways for conducting trails to find natural management strategies to combat multi drug resistant pathogens in horticulture, agriculture, and a

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印度克什米尔山谷 Morchella crassipes 的化学成分和抗菌特性

当今时代，野生大型真菌正被重点用于开发和发现新型生物活性化合物，以治疗农业、园艺和其他传染性疾病。有鉴于此，目前的研究工作旨在评估蘑菇的生化成分和药用特性。水提取物的植物化学筛选显示，除挥发油、树脂、类固醇和蒽醌外，还存在苷类、游离氨基酸和蛋白质、生物碱、碳水化合物、黄酮类、萜类、酚类化合物和单宁酸。不过，正己烷提取物中出现了苷类化合物、生物碱、挥发油、类固醇和萜类化合物，而所有其他植物化学物质均未检测到。气相色谱-质谱分析发现了三种主要的天然生物活性挥发性单萜类化合物，即 Neral、柠檬醛和环氧芳樟醇氧化物，它们具有众所周知的生物活性。甲醇提取物对测试的真菌菌株具有很强的抗真菌功效，如最高浓度下的蛹青霉（20.33±0.57 mm），其次是超微疫霉（15.33±0.76 mm）和黑曲霉（12.50±0.50 mm）。同样，金黄色葡萄球菌（15.16±0.76 mm）、胆汁沙门氏菌（14.33±0.57 mm）和大肠杆菌（13.66±0.57 mm）的抗菌效果也很明显。这些数据可提供有关生物活性代谢物的基线信息，并为开展追踪研究寻找自然管理策略开辟新途径，以对抗园艺、农业和生物技术领域的多重耐药性病原体。

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来源期刊

International journal of medicinal mushrooms 医学-药学

CiteScore

2.60

自引率

16.70%

发文量

审稿时长

6-12 weeks

期刊介绍： The rapid growth of interest in medicinal mushrooms research is matched by the large number of disparate groups that currently publish in a wide range of publications. The International Journal of Medicinal Mushrooms is the one source of information that will draw together all aspects of this exciting and expanding field - a source that will keep you up to date with the latest issues and practice. The International Journal of Medicinal Mushrooms published original research articles and critical reviews on a broad range of subjects pertaining to medicinal mushrooms, including systematics, nomenclature, taxonomy, morphology, medicinal value, biotechnology, and much more.