An Qi Xu, Nicolas Nguyen, Elie Bou Assi, Dang Khoa Nguyen
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Abstract
Locomotion is a goal-oriented behavior divided into three components: initiation (volitional or emotional), rhythmic limb movements, and intentional adjustment.1 Volitional initiation involves the frontal cortex and thalamus, guided by an individual's intention to move2-4. Emotional initiation is directed by the cingulate cortex and insula, leading to a sensation of urge to move. After initiation of the locomotion, rhythmic limb movements are coordinated by central pattern generators in the brainstem, spinal cord, and cerebellum.4 Our patient, a 45-year-old male who underwent an intracranial EEG study for left frontal lobe epilepsy, electrical stimulation of the anterior midcingulate cortex at 6 mA for 5 seconds repeatedly induced an “urge to move” and initiated a “getting-up” motion (Video 1), similar to the findings of Jackson et al.1 and Caruana et al.5
期刊介绍：
Epileptic Disorders is the leading forum where all experts and medical studentswho wish to improve their understanding of epilepsy and related disorders can share practical experiences surrounding diagnosis and care, natural history, and management of seizures.
Epileptic Disorders is the official E-journal of the International League Against Epilepsy for educational communication. As the journal celebrates its 20th anniversary, it will now be available only as an online version. Its mission is to create educational links between epileptologists and other health professionals in clinical practice and scientists or physicians in research-based institutions. This change is accompanied by an increase in the number of issues per year, from 4 to 6, to ensure regular diffusion of recently published material (high quality Review and Seminar in Epileptology papers; Original Research articles or Case reports of educational value; MultiMedia Teaching Material), to serve the global medical community that cares for those affected by epilepsy.
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