A Case Series of Choroidal and Orbital Neuroendocrine Tumors: Metastasis: Two Patients Treated With Peptide Radionuclide Therapy.

IF 1.7 4区医学 Q3 GASTROENTEROLOGY & HEPATOLOGY

Pancreas Pub Date : 2024-05-01 Epub Date: 2024-03-14 DOI:10.1097/MPA.0000000000002316

Tony Zibo Zhuang, Chris Bergstrom, Bassel F El-Rayes, Walid L Shaib

引用次数: 0

Abstract

Abstract: Neuroendocrine tumors (NETs) are rare cancers with heterogeneous histologies, response to treatments, and prognoses. Majority of these cancers originate in the gastrointestinal tract and metastasize to the liver. We report the cases of 5 patients with low-grade NET disease with rare metastases to the choroids. Two of the patients were treated with peptide receptor radionuclide therapy (lutetium 177 [ 177 Lu]). This is the first report confirming peptide radionuclide therapy safety in patients with low-grade NET with ocular metastases.

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脉络膜和眼眶神经内分泌肿瘤的病例系列：转移：2 名患者接受 PRRT 治疗。

摘要：神经内分泌肿瘤是一种罕见的癌症，其组织学、对治疗的反应和预后各不相同。这些癌症大多起源于胃肠道并转移至肝脏。我们报告了 5 例罕见转移至脉络膜的低级别神经内分泌肿瘤患者。其中两名患者接受了肽受体放射性核素疗法（Lutitium-177）。这是第一份证实PRRT对眼部转移的低级别NET患者具有安全性的报告。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pancreas 医学-胃肠肝病学

CiteScore

4.70

自引率

3.40%

发文量

289

审稿时长

1 months

期刊介绍： Pancreas provides a central forum for communication of original works involving both basic and clinical research on the exocrine and endocrine pancreas and their interrelationships and consequences in disease states. This multidisciplinary, international journal covers the whole spectrum of basic sciences, etiology, prevention, pathophysiology, diagnosis, and surgical and medical management of pancreatic diseases, including cancer.