Pulmonary metastasectomy after immune checkpoint inhibitors in malignant melanoma.

IF 0.7 Q3 Medicine
ASIAN CARDIOVASCULAR & THORACIC ANNALS Pub Date : 2024-09-01 Epub Date: 2024-03-25 DOI:10.1177/02184923241241583
Ichiro Sakanoue, Masatsugu Hamaji, Akihiro Ohsumi, Daisuke Nakajima, Hiroshi Date
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引用次数: 0

Abstract

The management of malignant melanoma with pulmonary metastases is controversial and occasionally requires multimodality management, including pulmonary metastasectomy after immune checkpoint inhibitors (ICIs). However, limited data are available on these patients. We described a case series of three consecutive patients who underwent pulmonary metastasectomy after ICIs for malignant melanoma and discussed the important characteristics of these patients. After pulmonary metastasectomy, none of the patients had recurrent pulmonary metastases, although extrapulmonary metastases were developed. Our case series suggests that pulmonary metastasectomy after ICIs may control pulmonary metastases in carefully selected patients with malignant melanoma.

恶性黑色素瘤患者使用免疫检查点抑制剂后的肺转移切除术
恶性黑色素瘤肺转移的治疗存在争议,有时需要多模式治疗,包括使用免疫检查点抑制剂(ICIs)后进行肺转移灶切除术。然而,有关这些患者的数据十分有限。我们描述了三例连续接受肺转移切除术的恶性黑色素瘤 ICIs 患者的病例系列,并讨论了这些患者的重要特征。肺转移灶切除术后,虽然出现了肺外转移,但没有一名患者出现复发性肺转移。我们的病例系列表明,对经过严格筛选的恶性黑色素瘤患者进行 ICI 后肺转移灶切除术可控制肺转移。
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来源期刊
CiteScore
1.30
自引率
0.00%
发文量
78
期刊介绍: The Asian Cardiovascular and Thoracic Annals is an international peer-reviewed journal pertaining to cardiovascular and thoracic medicine. Besides original clinical manuscripts, we welcome research reports, product reviews, reports of new techniques, and findings of special significance to Asia and the Pacific Rim. Case studies that have significant novel original observations, are instructive, include adequate methodological details and provide conclusions. Workshop proceedings, meetings and book reviews, letters to the editor, and meeting announcements are encouraged along with relevant articles from authors.
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