Air pollution, traffic noise, greenness, and temperature and the risk of incident type 2 diabetes: Results from the KORA cohort study

IF 3.3 Q2 ENVIRONMENTAL SCIENCES

Environmental Epidemiology Pub Date : 2024-03-11 DOI:10.1097/ee9.0000000000000302

Mahnaz Badpa, A. Schneider, Lars Schwettmann, Barbara Thorand, K. Wolf, A. Peters

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Abstract

Type 2 diabetes (T2D) is a major public health concern, and various environmental factors have been associated with the development of this disease. This study aimed to investigate the longitudinal effects of multiple environmental exposures on the risk of incident T2D in a German population-based cohort. We used data from the KORA cohort study (Augsburg, Germany) and assessed exposure to air pollutants, traffic noise, greenness, and temperature at the participants’ residencies. Cox proportional hazard models were used to analyze the associations with incident T2D, adjusting for potential confounders. Of 7736 participants included in the analyses, 10.5% developed T2D during follow-up (mean: 15.0 years). We found weak or no association between environmental factors and the risk of T2D, with sex and education level significantly modifying the effects of air pollutants. Our study contributes to the growing body of literature investigating the impact of environmental factors on T2D risks and suggests that the impact of environmental factors may be small.

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空气污染、交通噪音、绿化和温度与 2 型糖尿病发病风险：KORA 队列研究的结果

2 型糖尿病（T2D）是一个重大的公共卫生问题，而各种环境因素都与这种疾病的发生有关。本研究旨在调查多种环境暴露对德国人群队列中 2 型糖尿病发病风险的纵向影响。我们使用了 KORA 队列研究（德国奥格斯堡）的数据，评估了参与者居住地的空气污染物、交通噪音、绿化和温度暴露情况。在对潜在混杂因素进行调整后，我们使用 Cox 比例危险模型来分析与 T2D 发病的关系。在纳入分析的 7736 名参与者中，10.5% 的人在随访期间（平均 15.0 年）患上了终末期糖尿病。我们发现，环境因素与 T2D 风险之间的关系很弱或没有关系，而性别和教育水平会显著改变空气污染物的影响。我们的研究为越来越多的研究环境因素对 T2D 风险影响的文献做出了贡献，并表明环境因素的影响可能很小。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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