Seroprevalence of Human Cytomegalovirus among Aborted Women in Aden, Yemen

Abstract

Human cytomegalovirus (HCMV) is one member of Herpesviridae. It can cause serious complications in pregnant women and their fetuses. So, this study aims to determine the prevalence of IgG and IgM against HCMV among aborted women and other related factors in Aden–Yemen. An analytical cross-sectional study was conducted on 88 aborted women. Blood samples were collected and serum HCMV IgG and IgM were analyzed using ELISA. The overall prevalence of IgG and IgM of HCMV infections were 77.6% and 83.3%, respectively. Neither HCMV IgG nor IgM seroprevalence had significantly influenced by age, number of abortions, education level, trimesters, and other factors. It can be concluded that the seroprevalence IgG antibodies of HCMV infections among aborted women were slightly lower than those reported globally whereas the seroprevalence IgM antibodies were higher than most of the previous studies that performed globally. Other causative factors may also contribute to abortion among aborted women. Further research is required to detect the HCMV and other causative agents of abortion in Aden and other southern governments of Yemen using adequate sample size and new advanced techniques.