INFLUENCE OF LECTIN Paenibacillus polymyxa 1460 (LII) ON LIPID SPECTRUM PROFILE OF MALE RATS UNDER IN ANTIBIOTIC-ASSOCIATED DYSBACTERIOSIS

L.V. Karpunina, M.V. Proskuryakova
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Abstract

Paenibacillus polymyxa 1460 lectin (LII) isolated from the surface of soil nitrogen-fixing bacteria were shown to, contributes to the optimization of lipid metabolism in the organism of male albino rats with antibiotic-associated dysbacteriosis leading to the normal are important biochemical parameters in blood such as total cholesterol (TC), high density lipoproteins (HDL-C), low density lipoprotein (TC-LDL), lipoprotein very low density (XC-VLDL). The study of the effect of Paenibacillus polymyxa 1460 (LII) lectin on animal metabolism is important for understanding the mechanisms underlying the metabolic activity of these substances, and reveals the possibilities of its application in the practice of biomedical research with the prospect of its use as biologically active substances.
多粘杆菌 1460 (LII) 提取物对抗生素相关性白血病下雄性大鼠血脂谱的影响
研究表明,从土壤固氮菌表面分离出的多粘毛芽孢杆菌 1460(LII)凝集素有助于优化患有抗生素相关菌群失调症的雄性白化大鼠机体的脂质代谢,使其血液中的重要生化指标如总胆固醇(TC)、高密度脂蛋白(HDL-C)、低密度脂蛋白(TC-LDL)、极低密度脂蛋白(XC-VLDL)恢复正常。研究多粘杆菌 1460(LII)凝集素对动物新陈代谢的影响,对于了解这些物质的新陈代谢活性机制非常重要,并揭示了将其应用于生物医学研究实践的可能性,以及将其用作生物活性物质的前景。
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