Medicinal Mushrooms Cordyceps as a New Source of Bioactive Compounds and Their Complexation With Silver Ions

European Pharmaceutical Journal Pub Date : 2024-03-18 DOI:10.2478/afpuc-2024-0001

A. Uhrinová, Lucia Ungvarská Maľučká

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Abstract

Mushrooms from the genus Cordyceps are characterized by a wide range of biological effects due to the diverse amount of substances contained in them and are an important source of bioactive compounds. In China, mushrooms of the genus Cordyceps have been used as a medicinal preparation of traditional Chinese medicine for centuries. So far, a considerable number of studies have been conducted that focused on analyzing the effects of Cordyceps, which include their antioxidant, antibacterial, immunomodulatory, antidiabetic, antitumor, and many other effects. The ability of fungi to form complexes with various metals is also interesting. It is believed that polysaccharides are the main component of the extracts involved in the complexation with metals, after which their biological effects are improved and deepened. The work deals with the comparison of the antioxidant and antibacterial effects of Cordyceps extracts with extracts of this mushroom enriched with silver ions. Based on scientific studies, it is assumed that there is a complexation between the chemical compounds of the extracts and silver.

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作为生物活性化合物新来源的药用蘑菇冬虫夏草及其与银离子的络合物

冬虫夏草属蘑菇因含有多种物质而具有广泛的生物效应，是生物活性化合物的重要来源。在中国，冬虫夏草属蘑菇作为传统中药的药用制剂已有数百年的历史。迄今为止，已有大量研究重点分析了冬虫夏草的功效，包括抗氧化、抗菌、免疫调节、抗糖尿病、抗肿瘤等多种作用。真菌与各种金属形成复合物的能力也很有趣。据认为，多糖是参与与金属络合的提取物的主要成分，络合后其生物效应会得到改善和深化。这项研究比较了冬虫夏草提取物和富含银离子的冬虫夏草提取物的抗氧化和抗菌效果。根据科学研究推测，提取物的化学成分与银之间存在络合作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Pharmaceutical Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

CiteScore

0.60

自引率

0.00%

发文量

期刊介绍： European Pharmaceutical Journal publishes only original articles not previously published and articles that are not being considered or have not been submitted for publication elsewhere. If parts of the results have been published as conference abstract or elsewhere, it should be stated in references. The ethical standards of the Helsinki-Tokio Declaration should be kept. This should be mentioned in the Methods of manuscript. Reviews are published only on request. Authors, whose submitted research work was performed with the support of a company, should indicate this in Conflict of Interest.