Improvement of Organizational Measures for Detection and Diagnosing of Tuberculous Infection and Tuberculosis in Adolescents in the Republic of Kazakhstan

Q4 Medicine

Tuberculosis and Lung Diseases Pub Date : 2024-03-20 DOI:10.58838/2075-1230-2024-102-1-46-51

L. T. Eralieva, K. S. Serikbaeva, A. Rakisheva, Z. S. Bekbenbetova, O. G. Prikhodchenko

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引用次数: 0

Abstract

The objective: to improve organizational measures for detection and diagnosing of tuberculous infection and tuberculosis in adolescents in the Republic of Kazakhstan.Subjects and Methods. Screening was conducted among 27,648 adolescents aged 15-17 years from regions of the Republic of Kazakhstan with a high burden of tuberculosis. It was planned to use TRA tests and fluorography in parallel, while local doctors, district and school nurses, and nurses in vaccination rooms were preliminary trained by pediatric phthisiologists to perform the test, evaluate its results and monitor manifestations of adverse events (AEs) caused by TRA test.Results. 27,648 adolescents (aged 15-17 years) were given TRA test. No adverse events were observed during TRA skin test. Latent tuberculous infection was diagnosed in 320 (1.2%) adolescents. During further examination, 10 patients were diagnosed with drug susceptible pulmonary tuberculosis with no bacillary excretion. Based on the study results, to detect LTBI and tuberculosis in adolescents, in addition to fluorography examination, it is necessary to use TRA skin test with in the groups facing a high risk of tuberculosis.

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完善哈萨克斯坦共和国青少年结核感染和结核病检测与诊断的组织措施

目的：改善哈萨克斯坦共和国青少年结核感染和结核病检测与诊断的组织措施。对哈萨克斯坦共和国结核病高发地区的 27 648 名 15-17 岁青少年进行了筛查。当地医生、地区和学校护士以及疫苗接种室护士接受了儿科噬菌体学专家的初步培训，以进行检测、评估检测结果并监测由 TRA 检测引起的不良事件（AEs）表现。27648名青少年（15-17岁）接受了TRA测试。在 TRA 皮试过程中未发现任何不良反应。320名青少年（1.2%）被诊断为潜伏结核感染。在进一步检查中，有 10 名患者被确诊为对药物敏感的肺结核，且没有排出结核杆菌。根据研究结果，要检测青少年的迟发性肺结核和肺结核，除了荧光造影检查外，还有必要在肺结核高危人群中使用 TRA 皮试。

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来源期刊

Tuberculosis and Lung Diseases Medicine-Pulmonary and Respiratory Medicine

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The Journal is aimed for professional development of researchers, doctors, teachers of medical universities and training institutions. The Journal focuses on the presentation of results of research, case studies, issues of differential diagnostics and treatment in the phthisiologist’s practice, national programs on tuberculosis control in the Russian Federation, WHO strategies, discussion of prevention issues to stop transmission of TB/HIVco-infection, and extrapulmonary tuberculosis.