Retroperitoneal mixed neuroendocrine non-neuroendocrine neoplasm: A case report and review of literature.

IF 0.9 Q4 ONCOLOGY

Rare Tumors Pub Date : 2024-03-21 eCollection Date: 2024-01-01 DOI:10.1177/20363613241242383

John Adi Ashindoitiang, Victor Ikechukwu Canice Nwagbara, Theophilus Ugbem Ipeh, Ben Chukwu, Henry Olaleye Obanife, Alfred Ottoh Eyong, Maurice Efana Asuquo

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Abstract

The existence of both neuroendocrine and non-neuroendocrine histology in variable proportion in a lesion has been described by the World Health Organisation (WHO) as mixed neuroendocrine and non-neuroendocrine neoplasm (MiNEN). The pathogenesis of this tumour remains controversial but molecular studies point towards a common monoclonal origin. Tumours are classified as functioning and nonfunctioning based on substances secreted. The nonfunctioning tumours may be discovered due to its local effect. Presented is a 66-year-old male with an intra-abdominal mass, underwent laparotomy and excision biopsy with transient right lower limb lymphoedema. Histology confirmed retroperitoneal MiNEN with no evidence of tumour recurrence 12 months following surgery. MiNENs should be considered as a differential diagnosis in patients with intra-abdominal mass. Surgical resection is recommended as this may offer the best treatment option.

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腹膜后混合性神经内分泌非神经内分泌肿瘤：病例报告和文献综述。

世界卫生组织（WHO）将病变中存在不同比例的神经内分泌和非神经内分泌组织学称为混合性神经内分泌和非神经内分泌肿瘤（MiNEN）。这种肿瘤的发病机制仍存在争议，但分子研究表明其来源于一种常见的单克隆。肿瘤根据分泌的物质分为功能性和非功能性两种。非功能性肿瘤可能因其局部效应而被发现。患者是一名66岁的男性，腹腔内有肿块，接受了开腹手术和切除活检，并伴有一过性右下肢淋巴水肿。组织学检查证实为腹膜后米纳恩，术后 12 个月无肿瘤复发迹象。腹腔内肿块患者应将米网状细胞瘤视为鉴别诊断。建议进行手术切除，因为这可能是最佳治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Rare Tumors ONCOLOGY-

CiteScore

1.50

自引率

0.00%

发文量

审稿时长

15 weeks