Coherent Raman spectroscopy: Quo vadis?

IF 2.7 3区 化学 Q2 CHEMISTRY, ANALYTICAL
K. Brzozowski , W. Korona , A. Nowakowska , A. Borek-Dorosz , A. Pieczara , B. Orzechowska , A. Wislocka-Orlowska , Michael Schmitt , J. Popp , M. Baranska
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Abstract

Although the potential of Coherent Raman Spectroscopy (CRS) in the area of biomedicine, life sciences and material sciences has been well demonstrated, its wide-spread practical application is still rather limited. The two main CRS techniques are Coherent Anti-Stokes Raman Scattering (CARS) and Stimulated Raman Scattering (SRS) spectroscopy or microscopy. Here we present the current state of the art and challenges facing CRS. Although many technological challenges have been addressed to date, showing how to improve resolution, sensitivity and selectivity of CRS, significant efforts are still needed to increase the awareness of these techniques in the academic community, develop reliable protocols, and extend them to practical applications. For this purpose it is also necessary to initiate national and international research networks that can significantly contribute to the development of CRS approaches in areas that have so far made little use of CRS alongside other Raman spectroscopic methods. The purpose of this perspective paper is to present the current state-of-the-art of CRS with a historical background, assess the challenges and present some future development visions.

相干拉曼光谱:何去何从?
尽管相干拉曼光谱(CRS)在生物医学、生命科学和材料科学领域的潜力已得到充分展示,但其广泛的实际应用仍然相当有限。相干反斯托克斯拉曼散射(CARS)和受激拉曼散射(SRS)光谱或显微镜是两种主要的相干拉曼光谱技术。在此,我们将介绍相干反斯托克斯拉曼散射的技术现状和面临的挑战。尽管迄今为止已经解决了许多技术难题,展示了如何提高 CRS 的分辨率、灵敏度和选择性,但仍需做出巨大努力,以提高学术界对这些技术的认识,开发可靠的协议,并将其推广到实际应用中。为此,还有必要启动国家和国际研究网络,在迄今为止还很少使用 CRS 和其他拉曼光谱方法的领域,大力促进 CRS 方法的发展。本视角论文的目的是结合历史背景介绍当前 CRS 的最新进展,评估面临的挑战,并提出一些未来的发展愿景。
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来源期刊
Vibrational Spectroscopy
Vibrational Spectroscopy 化学-分析化学
CiteScore
4.70
自引率
4.00%
发文量
103
审稿时长
52 days
期刊介绍: Vibrational Spectroscopy provides a vehicle for the publication of original research that focuses on vibrational spectroscopy. This covers infrared, near-infrared and Raman spectroscopies and publishes papers dealing with developments in applications, theory, techniques and instrumentation. The topics covered by the journal include: Sampling techniques, Vibrational spectroscopy coupled with separation techniques, Instrumentation (Fourier transform, conventional and laser based), Data manipulation, Spectra-structure correlation and group frequencies. The application areas covered include: Analytical chemistry, Bio-organic and bio-inorganic chemistry, Organic chemistry, Inorganic chemistry, Catalysis, Environmental science, Industrial chemistry, Materials science, Physical chemistry, Polymer science, Process control, Specialized problem solving.
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