[Differential diagnosis in food allergy].

Liziane Nunes de Castilho Santos
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Abstract

It is important to establish the differential diagnosis of food allergy with other disorders, for example: toxic reactions that occur in any person exposed to a sufficient amount of some allergen, and non-toxic reactions that depend on individual susceptibility (food allergy or intolerance). The differential diagnosis is decisive to establish the appropriate treatment. Food intolerance involves adverse reactions to foods without any immunological response involved, and commonly manifests with gastrointestinal symptoms (malaise, abdominal pain or diarrhea). Food allergy is an exaggerated reaction of the immune system, often mediated by IgE, that can trigger serious symptoms (hives, inflammation, respiratory distress, even anaphylaxis). The complex thing is because the symptoms sometimes overlap. To establish an accurate diagnosis, exhaustive clinical evaluation, laboratory tests and, in some cases, controlled provocation tests are required. It is important to understand these distinctions, because treatment and management vary significantly. Food intolerance involves the elimination or reduction of the food that triggers the allergic reaction and requires rigorous measures (complete avoidance of the allergen and availability of epinephrine in cases of severe reactions).

[食物过敏的鉴别诊断]。
重要的是要将食物过敏与其他疾病进行鉴别诊断,例如:任何接触到足量某种过敏原的人都会发生的毒性反应,以及取决于个体易感性(食物过敏或不耐受)的非毒性反应。鉴别诊断对确定适当的治疗方法起着决定性作用。食物不耐受包括对食物的不良反应,不涉及任何免疫反应,通常表现为胃肠道症状(不适、腹痛或腹泻)。食物过敏是免疫系统的一种夸张反应,通常由 IgE 介导,可引发严重症状(荨麻疹、炎症、呼吸窘迫,甚至过敏性休克)。之所以复杂,是因为症状有时会重叠。要确定准确的诊断,需要进行详尽的临床评估、实验室检测,有时还需要进行控制性激发试验。了解这些区别非常重要,因为治疗和管理方法大不相同。食物不耐受涉及消除或减少引发过敏反应的食物,需要采取严格的措施(完全避免接触过敏原,严重反应时可使用肾上腺素)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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