Post Trauma Acinetobacter Baumanii Meningitis Treatment Approach.

Cem Erdoğan, Zeynep Betul Balcioglu, Isa Seida, Denız Kizilaslan
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Abstract

A. baumannii, which is said to be associated with nosocomial infections is considered a significant mortality risk if not adequately addressed. A. baumannii infections typically occur in the aftermath of surgery or trauma. Our patient developed complicated A. baumannii meningitis with lateral ventriculitis and a lumbar abscess post surgery after suffering from a fall. The patient was treated with a 21-day regimen of intrathecally administered colistin and polymyxin B. Following this therapeutic period, the patient's condition improved, ultimately leading to successful recovery and subsequent discharge. This case report serves to highlight the ability of intrathecal administration of antibiotics, that normally have limited potential of crossing the blood-brain-barrier, to lead to improved survival outcomes in multi-drug resistant nosocomial meningitis.

创伤后鲍曼不动杆菌脑膜炎治疗方法。
据说鲍曼尼氏菌与医院内感染有关,如果不加以适当处理,会有很大的死亡风险。鲍曼尼菌感染通常发生在手术或创伤后。我们的患者在手术后因摔倒而患上了复杂的鲍曼不动杆菌脑膜炎,并伴有侧脑室炎和腰部脓肿。患者接受了为期 21 天的肠内注射秋水仙碱和多粘菌素 B 的治疗。治疗期结束后,患者的病情有所好转,最终成功康复出院。本病例报告强调了鞘内给药抗生素(通常只能有限地穿过血脑屏障)能够改善耐多药鼻疽性脑膜炎患者的生存状况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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