Gut Microbiota Targeted Approach by Natural Products in Diabetes Management: An Overview.

IF 4.6 3区医学 Q1 NUTRITION & DIETETICS

Current Nutrition Reports Pub Date : 2024-06-01 Epub Date: 2024-03-18 DOI:10.1007/s13668-024-00523-1

Priyanka Sati, Praveen Dhyani, Eshita Sharma, Dharam Chand Attri, Arvind Jantwal, Rajni Devi, Daniela Calina, Javad Sharifi-Rad

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引用次数: 0

Abstract

Purpose of review: This review delves into the complex interplay between obesity-induced gut microbiota dysbiosis and the progression of type 2 diabetes mellitus (T2DM), highlighting the potential of natural products in mitigating these effects. By integrating recent epidemiological data, we aim to provide a nuanced understanding of how obesity exacerbates T2DM through gut flora alterations.

Recent findings: Advances in research have underscored the significance of bioactive ingredients in natural foods, capable of restoring gut microbiota balance, thus offering a promising approach to manage diabetes in the context of obesity. These findings build upon the traditional use of medicinal plants in diabetes treatment, suggesting a deeper exploration of their mechanisms of action. This comprehensive manuscript underscores the critical role of targeting gut microbiota dysbiosis in obesity-related T2DM management and by bridging traditional knowledge with current scientific evidence; we highlighted the need for continued research into natural products as a complementary strategy for comprehensive diabetes care.

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天然产品在糖尿病管理中的肠道微生物群靶向疗法：概述。

综述的目的：这篇综述深入探讨了肥胖引起的肠道微生物群失调与 2 型糖尿病（T2DM）进展之间复杂的相互作用，强调了天然产品在减轻这些影响方面的潜力。通过整合最近的流行病学数据，我们旨在提供对肥胖如何通过肠道菌群改变加剧 T2DM 的细致理解：研究进展凸显了天然食品中生物活性成分的重要性，这些成分能够恢复肠道微生物群的平衡，从而为肥胖情况下的糖尿病管理提供了一种前景广阔的方法。这些发现建立在药用植物治疗糖尿病的传统基础上，建议对其作用机制进行更深入的探索。这份内容全面的手稿强调了针对肠道微生物群失调在肥胖相关的 T2DM 管理中的关键作用，并通过将传统知识与当前的科学证据相结合；我们强调了继续研究天然产品作为糖尿病综合护理补充策略的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Nutrition Reports Agricultural and Biological Sciences-Food Science

CiteScore

7.70

自引率

2.00%

发文量

期刊介绍： This journal aims to provide comprehensive review articles that emphasize significant developments in nutrition research emerging in recent publications. By presenting clear, insightful, balanced contributions by international experts, the journal intends to discuss the influence of nutrition on major health conditions such as diabetes, cardiovascular disease, cancer, and obesity, as well as the impact of nutrition on genetics, metabolic function, and public health. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas across the field. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an Editorial Board of more than 25 internationally diverse members reviews the annual table of contents, suggests topics of special importance to their country/region, and ensures that topics and current and include emerging research.