Tissue engineering: chondrocytes and cartilage.

Arthritis research Pub Date : 2002-01-01 Epub Date: 2002-05-09 DOI:10.1186/ar561
Tim Hardingham, Simon Tew, Alan Murdoch
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引用次数: 0

Abstract

Tissue engineering offers new strategies for developing treatments for the repair and regeneration of damaged and diseased tissues. These treatments, using living cells, will exploit new developments in understanding the principles in cell biology that control and direct cell function. Arthritic diseases that affect so many people and have a major impact on the quality of life provide an important target for tissue engineering. Initial approaches are in cartilage repair; in our own programme we are elucidating the signals required by chondrocytes to promote new matrix assembly. These principles will extend to other tissues of the musculoskeletal system, including the repair of bone, ligament and tendon.

组织工程:软骨细胞和软骨。
组织工程学为开发修复和再生受损和患病组织的治疗方法提供了新策略。这些使用活细胞的治疗方法将利用在了解细胞生物学中控制和指导细胞功能的原理方面取得的新进展。关节炎疾病影响着许多人,并对生活质量产生重大影响,是组织工程学的一个重要目标。最初的方法是软骨修复;在我们自己的计划中,我们正在阐明软骨细胞促进新基质组装所需的信号。这些原理将扩展到肌肉骨骼系统的其他组织,包括骨、韧带和肌腱的修复。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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