Case series: Older age bipolar disorder with dementia

Psychiatry research case reports Pub Date : 2024-03-08 DOI:10.1016/j.psycr.2024.100217

Yasuhito Nagai , Takumi Hirose , Shuntaro Natsume , Takao Saida , Narihiro Orimo , Eiji Kirino

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Abstract

Most patients with bipolar disorder do not develop the symptoms until 18 years. With peak onset of 20–40 years, about 90% of cases are reported to have onset prior to age 50 years. Population-based surveys revealed a decrease in the prevalence of bipolar disorder with age, but 6–8% of all new cases of bipolar disorder developing in persons ≥60 years of age The elderly bipolar disorder patients often comorbid with dementia, presented many psychiatric symptoms. This condition is difficult to distinguish from overactivity, agitation, and excitation in behavior and psychological symptoms of dementia and delirium. Therefore, older age bipolar disorder is not well understood and are under- investigated. Herein, we presented three cases of older age bipolar disorder with dementia to discuss the possibility of biological overlaps between BD and dementia, as well as treatment options.

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病例系列：老年双相情感障碍伴痴呆症

大多数躁郁症患者在 18 岁之前不会出现症状。据报道，躁郁症的发病高峰期为 20-40 岁，约 90% 的病例在 50 岁之前发病。基于人口的调查显示，躁郁症的发病率随着年龄的增长而下降，但在所有新发的躁郁症病例中，6%-8%发生在年龄≥60 岁的人群中。这种情况很难与痴呆和谵妄的过度活跃、激动、兴奋等行为和心理症状区分开来。因此，人们对老年躁狂症的了解并不多，对其研究也不足。在此，我们介绍了三例老年躁狂症合并痴呆症的病例，以探讨老年躁狂症与痴呆症之间生物学重叠的可能性以及治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Psychiatry research case reports Medicine and Dentistry (General)

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