Carotid Stenosis and Stroke: Historical Perspectives Leading to Current Challenges.

IF 2.9 4区医学 Q2 CLINICAL NEUROLOGY

Canadian Journal of Neurological Sciences Pub Date : 2025-01-01 Epub Date: 2024-03-11 DOI:10.1017/cjn.2024.40

David M Pelz, Allan J Fox, J David Spence, Stephen P Lownie

引用次数: 0

Abstract

The carotid artery is unique; it is the only vessel to bifurcate into a bulb larger than itself. The history of its anatomic description, understanding of its pathophysiology and evolution of its imaging are relevant to current controversies regarding measurement of stenosis, surgical/endovascular therapies and medical management of carotid stenosis in stroke prevention. Treatment decisions on millions of symptomatic and asymptomatic patients are routinely based on information from clinical trials from over 30 years ago. This article briefly summarizes the highlights of past research in key areas and discuss how they led to current challenges of diagnosis and treatment.

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颈动脉狭窄与中风：从历史角度看当前面临的挑战。

颈动脉是独一无二的；它是唯一一条分叉成比自身更大的球部的血管。对其解剖学描述的历史、对其病理生理学的理解以及对其成像的演变都与当前有关测量颈动脉狭窄、手术/血管内治疗以及预防中风的颈动脉狭窄药物治疗的争议有关。数百万无症状和无症状患者的治疗决策通常基于 30 多年前的临床试验信息。本文简要总结了过去在关键领域的研究重点，并讨论了这些研究如何导致当前诊断和治疗的挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Canadian Journal of Neurological Sciences 医学-临床神经学

CiteScore

4.30

自引率

3.30%

发文量

330

审稿时长

4-8 weeks

期刊介绍： Canadian Neurological Sciences Federation The Canadian Journal of Neurological Sciences is the official publication of the four member societies of the Canadian Neurological Sciences Federation -- Canadian Neurological Society (CNS), Canadian Association of Child Neurology (CACN), Canadian Neurosurgical Society (CNSS), Canadian Society of Clinical Neurophysiologists (CSCN). The Journal is a widely circulated internationally recognized medical journal that publishes peer-reviewed articles. The Journal is published in January, March, May, July, September, and November in an online only format. The first Canadian Journal of Neurological Sciences (the Journal) was published in 1974 in Winnipeg. In 1981, the Journal became the official publication of the member societies of the CNSF.