Monitoring of Caffeine Consumption Effect on Skin Blood Properties by Diffuse Reflectance Spectroscopy.

IF 1.9 4区医学 Q3 PHYSIOLOGY

Physiological research Pub Date : 2024-03-11 DOI:10.33549/physiolres.935138

M Milanic, R Hren, J Stergar, U Simoncic

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Abstract

Caffeine is the most widely consumed psychoactive substance worldwide, affecting numerous tissues and organs, with notable impacts on the central nervous system, heart, and blood vessels. The effect of caffeine on vascular smooth muscle cells is an initial transient contraction followed by significant vasodilatation. In this study we investigate the use of diffuse reflectance spectroscopy (DRS) for monitoring of vascular changes in human skin induced by caffeine consumption. DRS spectra were recorded on volar sides of the forearms of eight healthy volunteers at time intervals of 0, 30, 60, 120, and 180 min after consumption of caffeine, while one subject served as a negative control. Analytical diffusion approximation solutions for diffuse reflectance from three-layer structures were used to assess skin composition (e.g. dermal blood volume fraction and oxygen saturation) by fitting these solutions to experimental data. The results demonstrate that cutaneous vasodynamics induced by caffeine consumption can be monitored by DRS, while changes in the control subject not consuming caffeine were insignificant.

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利用漫反射光谱监测咖啡因摄入对皮肤血液特性的影响

咖啡因是全球消费最广泛的精神活性物质，会影响许多组织和器官，对中枢神经系统、心脏和血管的影响尤为明显。咖啡因对血管平滑肌细胞的影响是最初的短暂收缩，随后是明显的血管舒张。在本研究中，我们研究了利用漫反射光谱（DRS）监测人体皮肤因摄入咖啡因而引起的血管变化。我们在八名健康志愿者摄入咖啡因后的 0、30、60、120 和 180 分钟的时间间隔内记录了他们前臂外侧的 DRS 光谱，其中一名受试者作为阴性对照。通过将三层结构的漫反射分析扩散近似解与实验数据拟合，评估皮肤成分（如真皮血容量分数和氧饱和度）。结果表明，通过 DRS 可以监测摄入咖啡因引起的皮肤血管动力学变化，而未摄入咖啡因的对照组的变化并不明显。

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来源期刊

Physiological research 医学-生理学

CiteScore

4.00

自引率

4.80%

发文量

108

审稿时长

3 months

期刊介绍： Physiological Research is a peer reviewed Open Access journal that publishes articles on normal and pathological physiology, biochemistry, biophysics, and pharmacology. Authors can submit original, previously unpublished research articles, review articles, rapid or short communications. Instructions for Authors - Respect the instructions carefully when submitting your manuscript. Submitted manuscripts or revised manuscripts that do not follow these Instructions will not be included into the peer-review process. The articles are available in full versions as pdf files beginning with volume 40, 1991. The journal publishes the online Ahead of Print /Pre-Press version of the articles that are searchable in Medline and can be cited.