Recent Advances in Electrochemical and Nanophotonic Biosensors for SARS-CoV-2 Detection

IF 5.5 3区 工程技术 Q1 BIOCHEMICAL RESEARCH METHODS
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引用次数: 0

Abstract

The contagious respiratory illness coronavirus disease 2019 (COVID-19) has had an unprecedented impact on both global health and society, causing a global pandemic due to its rapid transmission. The emergence of numerous variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) underscores the critical importance of accurately diagnosing variants of concern (VOCs). Viruses have demonstrated a remarkable ability to evolve and adapt to their environments. Therefore, it is crucial to develop effective diagnostic methods that provide rapid, high sensitivity, and selectivity in a point-of-care (PoC) format, meeting the vital need for detecting and addressing emerging new viruses in the future. With the development of nanotechnology and biotechnology, there have been innovations in rapid, multiplexed, and portable sensors with high sensitivity and specificity. In this review, we discuss the fundamental properties of the SARS-CoV-2 virus, conventional diagnostic methods, and recent developments from the perspective of electrochemical- and nanophotonic-based SARS-CoV-2 biosensors, including our recent work.

用于检测 SARS-CoV-2 的电化学和纳米光子生物传感器的最新进展
摘要 2019 年传染性呼吸道疾病冠状病毒病(COVID-19)对全球健康和社会产生了前所未有的影响,由于其传播速度快,造成了全球大流行。严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)众多变种的出现凸显了准确诊断相关变种(VOCs)的极端重要性。病毒显示出进化和适应环境的非凡能力。因此,开发出快速、高灵敏度、高选择性的有效诊断方法至关重要,这种诊断方法可在护理点(PoC)形式下进行,以满足检测和应对未来新出现的病毒的迫切需要。随着纳米技术和生物技术的发展,具有高灵敏度和特异性的快速、多路复用和便携式传感器也有了创新。在这篇综述中,我们将从基于电化学和纳米光子的 SARS-CoV-2 生物传感器的角度,讨论 SARS-CoV-2 病毒的基本特性、传统诊断方法和最新进展,包括我们最近的工作。
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来源期刊
BioChip Journal
BioChip Journal 生物-生化研究方法
CiteScore
7.70
自引率
16.30%
发文量
47
审稿时长
6-12 weeks
期刊介绍: BioChip Journal publishes original research and reviews in all areas of the biochip technology in the following disciplines, including protein chip, DNA chip, cell chip, lab-on-a-chip, bio-MEMS, biosensor, micro/nano mechanics, microfluidics, high-throughput screening technology, medical science, genomics, proteomics, bioinformatics, medical diagnostics, environmental monitoring and micro/nanotechnology. The Journal is committed to rapid peer review to ensure the publication of highest quality original research and timely news and review articles.
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