Surgical Margins in Musculoskeletal Sarcoma.

IF 1.7 Q2 SURGERY

JBJS Reviews Pub Date : 2024-03-06 eCollection Date: 2024-03-01 DOI:10.2106/JBJS.RVW.23.00224

Julia C Quirion, Samuel R Johnson, Brooke L Kowalski, Jennifer L Halpern, Herbert S Schwartz, Ginger E Holt, Carlos Prieto-Granada, Reena Singh, Justin M M Cates, Brian P Rubin, Nathan W Mesko, Lukas M Nystrom, Joshua M Lawrenz

引用次数: 0

Abstract

» Negative margin resection of musculoskeletal sarcomas is associated with reduced risk of local recurrence.» There is limited evidence to support an absolute margin width of soft tissue or bone that correlates with reduced risk of local recurrence.» Factors intrinsic to the tumor, including histologic subtype, grade, growth pattern and neurovascular involvement impact margin status and local recurrence, and should be considered when evaluating a patient's individual risk after positive margins.» Appropriate use of adjuvant therapy, critical analysis of preoperative advanced cross-sectional imaging, and the involvement of a multidisciplinary team are essential to obtain negative margins when resecting sarcomas.

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肌肉骨骼肉瘤的手术边缘。

"肌肉骨骼肉瘤的负边缘切除与局部复发风险降低有关"。支持软组织或骨骼绝对边缘宽度与降低局部复发风险相关的证据有限"。肿瘤的内在因素，包括组织学亚型、分级、生长模式和神经血管受累等，都会影响边缘状态和局部复发，在评估患者边缘阳性后的个体风险时应加以考虑。"在切除肉瘤时，适当使用辅助治疗、严格分析术前先进的横断面成像以及多学科团队的参与对于获得阴性边缘至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

JBJS Reviews SURGERY-

CiteScore

4.40

自引率

4.30%

发文量

132

期刊介绍： JBJS Reviews is an innovative review journal from the publishers of The Journal of Bone & Joint Surgery. This continuously published online journal provides comprehensive, objective, and authoritative review articles written by recognized experts in the field. Edited by Thomas A. Einhorn, MD, and a distinguished Editorial Board, each issue of JBJS Reviews, updates the orthopaedic community on important topics in a concise, time-saving manner, providing expert insights into orthopaedic research and clinical experience. Comprehensive reviews, special features, and integrated CME provide orthopaedic surgeons with valuable perspectives on surgical practice and the latest advances in the field within twelve subspecialty areas: Basic Science, Education & Training, Elbow, Ethics, Foot & Ankle, Hand & Wrist, Hip, Infection, Knee, Oncology, Pediatrics, Pain Management, Rehabilitation, Shoulder, Spine, Sports Medicine, Trauma.