Naked mole-rat ovaries allow investigation of ovarian reserve in vitro germ cell expansion, and oocyte IVM within a single sample

IF 3.7 3区生物学 Q1 DEVELOPMENTAL BIOLOGY

Reproduction Pub Date : 2024-03-01 DOI:10.1530/rep-23-0459

Gretchen M Rosado, Ana Martinez-Marchal, Mariela Faykoo-Martinez, Melissa M. Holmes, Miguel Angel Angel Brieño-Enriquez

引用次数: 0

Abstract

Recently, we described that in the naked mole-rat ovary it is possible to study the ovarian reserve and the mitotic expansion of the germ cell postnatally. Herein, we show oocyte in vitro maturation and in vitro germ cell expansion using the same ovary.

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裸鼹鼠卵巢可用于研究卵巢储备、体外生殖细胞扩增和单个样本中的卵母细胞 IVM

最近，我们描述了在裸鼹鼠卵巢中研究卵巢储备和产后生殖细胞有丝分裂扩增的可能性。在这里，我们用同一个卵巢展示了卵母细胞的体外成熟和生殖细胞的体外扩增。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Reproduction 生物-发育生物学

CiteScore

7.40

自引率

2.60%

发文量

199

审稿时长

4-8 weeks

期刊介绍： Reproduction is the official journal of the Society of Reproduction and Fertility (SRF). It was formed in 2001 when the Society merged its two journals, the Journal of Reproduction and Fertility and Reviews of Reproduction. Reproduction publishes original research articles and topical reviews on the subject of reproductive and developmental biology, and reproductive medicine. The journal will consider publication of high-quality meta-analyses; these should be submitted to the research papers category. The journal considers studies in humans and all animal species, and will publish clinical studies if they advance our understanding of the underlying causes and/or mechanisms of disease. Scientific excellence and broad interest to our readership are the most important criteria during the peer review process. The journal publishes articles that make a clear advance in the field, whether of mechanistic, descriptive or technical focus. Articles that substantiate new or controversial reports are welcomed if they are noteworthy and advance the field. Topics include, but are not limited to, reproductive immunology, reproductive toxicology, stem cells, environmental effects on reproductive potential and health (eg obesity), extracellular vesicles, fertility preservation and epigenetic effects on reproductive and developmental processes.