C. Tsimakidi, M. Gontika, D. Gkougka, K Rizonaki, S. Fanouraki, C. Kotsalis
{"title":"Interferon-beta-1a induced retinopathy in a 14-year-old female patient with multiple sclerosis","authors":"C. Tsimakidi, M. Gontika, D. Gkougka, K Rizonaki, S. Fanouraki, C. Kotsalis","doi":"10.1016/j.nerep.2024.100202","DOIUrl":null,"url":null,"abstract":"<div><p>Interferon (INF) b-1a is a widely used medication, administered as first-line treatment in adult and pediatric patients with multiple sclerosis (MS). Common adverse reactions include flu-like symptoms, skin changes, allergic reactions and depression.</p><p>Interferon-induced retinopathy commonly arises in HCV patients treated with INFa, but has rarely been associated with IFNb administration in adults.</p><p>We present a 14-year-old female, newly diagnosed with MS, that presented with interferon-induced retinopathy, five months after IFNb-1a initiation. The medication was discontinued with complete recovery.</p><p>To our knowledge, this is the first reported case of IFNb-induced retinopathy in a pediatric patient.</p></div>","PeriodicalId":100950,"journal":{"name":"Neuroimmunology Reports","volume":"5 ","pages":"Article 100202"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667257X24000032/pdfft?md5=3a9f94152296c3b5fabb00d9bda3d27b&pid=1-s2.0-S2667257X24000032-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuroimmunology Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667257X24000032","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Interferon (INF) b-1a is a widely used medication, administered as first-line treatment in adult and pediatric patients with multiple sclerosis (MS). Common adverse reactions include flu-like symptoms, skin changes, allergic reactions and depression.
Interferon-induced retinopathy commonly arises in HCV patients treated with INFa, but has rarely been associated with IFNb administration in adults.
We present a 14-year-old female, newly diagnosed with MS, that presented with interferon-induced retinopathy, five months after IFNb-1a initiation. The medication was discontinued with complete recovery.
To our knowledge, this is the first reported case of IFNb-induced retinopathy in a pediatric patient.