Aqyl Hanif Abdillah, Ahmad Aziz Multazam Rangkuti, Dimas Pangestu, Salsabila Az-Zahra, Supiono Supiono
{"title":"Efficacy and safety of quinolones as potential first line therapy in pulmonary tuberculosis: a meta-analysis.","authors":"Aqyl Hanif Abdillah, Ahmad Aziz Multazam Rangkuti, Dimas Pangestu, Salsabila Az-Zahra, Supiono Supiono","doi":"10.3897/folmed.66.e115239","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Tuberculosis is an infectious disease that continues to plague the world today, causing concerns due to its high mortality rate. The therapy regimens used for the treatment of tuberculosis today have demonstrated high efficacy and safety, potentially reducing the disease's burden, but the use of some standardized medications has caused many resistances to emerge. Over the last decade, researchers have been looking for suitable alternatives, with quinolones emerging as the most promising candidate due to their efficacy, safety, and availability. However, their efficacy as a first-line treatment remains debatable.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 1","pages":"26-34"},"PeriodicalIF":0.0000,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Folia medica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3897/folmed.66.e115239","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Dentistry","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Tuberculosis is an infectious disease that continues to plague the world today, causing concerns due to its high mortality rate. The therapy regimens used for the treatment of tuberculosis today have demonstrated high efficacy and safety, potentially reducing the disease's burden, but the use of some standardized medications has caused many resistances to emerge. Over the last decade, researchers have been looking for suitable alternatives, with quinolones emerging as the most promising candidate due to their efficacy, safety, and availability. However, their efficacy as a first-line treatment remains debatable.
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