Maria Paula Maziero, Natalia P Rocha, Antonio L Teixeira
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引用次数: 0
Abstract
Psychosis and hyperactive behaviors, such as agitation and wandering, affect a significant proportion of patients with Alzheimer's disease (AD). These symptoms are often treated with antipsychotics, usually in an off-label approach. This mini-review provides an updated perspective on the pharmacological approach for the neuropsychiatric symptoms (NPS) in AD. The results of new studies have provided a better understanding of AD-related NPS management, but high-quality evidence still needs to be obtained. Herein, we argue for a more cautious approach to the use of antipsychotics in AD and highlight the importance of exploring alternative treatments for NPS. By doing so, we can ensure that patients with AD receive optimal care that is both effective and safe.
阿尔茨海默病中的抗精神病药物：抗精神病药物在阿尔茨海默病中的应用：现状与治疗替代方案》（Current Status and Therapeutic Alternatives.
很大一部分阿尔茨海默病患者会出现精神错乱和多动行为，如激动和徘徊。这些症状通常采用抗精神病药物治疗，通常是标示外治疗。本篇微型综述从最新角度介绍了治疗阿尔茨海默病（AD）神经精神症状（NPS）的药物疗法。新研究的结果使人们对与 AD 相关的 NPS 治疗有了更好的了解，但仍需获得高质量的证据。在此，我们主张在 AD 中使用抗精神病药物时应更加谨慎，并强调探索 NPS 替代疗法的重要性。通过这样做，我们可以确保AD患者得到既有效又安全的最佳治疗。
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