The effect of dopamine antagonists in spontaneous and tardive dyskinesia.

R Fog
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引用次数: 2

Abstract

Dopamine antagonists are effective in suppressing hyperkinetic symptoms in patients with tardive dyskinesia, spontaneous oral dyskinesia, Huntington's chorea, and Gilles de la Tourette's syndrome. These neuroleptics have no curative effect upon the conditions and may even aggravate symptoms in the long term. In many cases a single neuroleptic drug may lose its effect. A more lasting effect may be obtained by combining drugs with pre- and postsynaptic antidopamine effects.

多巴胺拮抗剂在自发性和迟发性运动障碍中的作用。
多巴胺拮抗剂可有效抑制迟发性运动障碍、自发性口腔运动障碍、亨廷顿舞蹈病和图雷特吉尔综合征患者的多动症状。这些抗精神病药对病情没有疗效,长期甚至可能加重症状。在许多情况下,单一的抗精神病药物可能失去其效果。通过将药物与突触前和突触后抗多巴胺作用联合使用,可以获得更持久的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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