The predictive value of triglyceride-glucose index for assessing the severity and MACE of premature coronary artery disease.

IF 0.7 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiovascular Journal of Africa Pub Date : 2024-02-21 DOI:10.5830/CVJA-2023-060

Ling Yang, Yu Peng, Zheng Zhang

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引用次数: 0

Abstract

Objective: The aim of this study was to investigate the predictive value of the triglyceride-glucose (TyG) index to assess the severity and major adverse cardiovascular events (MACE) of patients in hospital with premature coronary artery disease (PCAD).

Methods: A total of 300 patients with PCAD, diagnosed by coronary angiography (CAG), were enrolled in this study. According to the tertiles of TyG index, the 300 patients were divided into a T1 (n = 100), T2 (n = 100) and T3 group (n = 100). According to the presence or absence of MACE, the 300 patients were divided into a MACE (n = 80) and a non-MACE group (n = 220). The patients' clinical data were compared between the groups, the relationship between TyG index and the severity of PCAD and MACE were analysed through multivariable logistic regression analysis, and their predictive value was detected using receiver operating characteristic (ROC) curves.

Results: Multivariable logistic regression analysis showed that the TyG index was an independent risk factor for the severity of PCAD and MACE. The area under the ROC curve was 0.833 and 0.807, respectively (all p < 0.05).

Conclusion: The TyG index was independently associated with the severity of PCAD and MACE, and had a good predictive value.

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甘油三酯-葡萄糖指数对评估早发冠心病严重程度和 MACE 的预测价值。

研究目的本研究旨在探讨甘油三酯-葡萄糖（TyG）指数对评估早发冠状动脉疾病（PCAD）住院患者的严重程度和主要不良心血管事件（MACE）的预测价值：本研究共纳入 300 名经冠状动脉造影术（CAG）确诊的 PCAD 患者。根据 TyG 指数的三等分，300 名患者被分为 T1 组（100 人）、T2 组（100 人）和 T3 组（100 人）。根据有无MACE，300名患者被分为MACE组（n = 80）和无MACE组（n = 220）。比较两组患者的临床数据，通过多变量逻辑回归分析TyG指数与PCAD严重程度和MACE之间的关系，并利用接收器操作特征曲线（ROC）检测其预测价值：多变量逻辑回归分析表明，TyG指数是PCAD和MACE严重程度的独立危险因素。ROC曲线下面积分别为0.833和0.807（P均<0.05）：结论：TyG指数与PCAD和MACE的严重程度独立相关，具有良好的预测价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cardiovascular Journal of Africa CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： The Cardiovascular Journal of Africa (CVJA) is an international peer-reviewed journal that keeps cardiologists up to date with advances in the diagnosis and treatment of cardiovascular disease. Topics covered include coronary disease, electrophysiology, valve disease, imaging techniques, congenital heart disease (fetal, paediatric and adult), heart failure, surgery, and basic science.