KASTURI ORANGE PEEL (CITRUS MICROCARPA BUNGE) ESSENTIAL OIL: CHEMICAL PROFILE, FORMULATION AS ROLL-ON AROMATHERAPY AND ITS EVALUATION

Q2 Pharmacology, Toxicology and Pharmaceutics
Yahdian Rasyadi, Wida Ningsih, Wanda Pranca Mulya, Dini Hanifa
{"title":"KASTURI ORANGE PEEL (CITRUS MICROCARPA BUNGE) ESSENTIAL OIL: CHEMICAL PROFILE, FORMULATION AS ROLL-ON AROMATHERAPY AND ITS EVALUATION","authors":"Yahdian Rasyadi, Wida Ningsih, Wanda Pranca Mulya, Dini Hanifa","doi":"10.22159/ijap.2024.v16s1.28","DOIUrl":null,"url":null,"abstract":"Objective: Kasturi orange (Citrus microcarpa Bunge) is widely cultivated and consumed in Indonesia. The fruit's flesh is a good source of vitamin C. Essential oil of kasturi orange peel is one of the ingredients used as a raw material for aromatherapy roll-on preparations. Roll-on aromatherapy is currently widely used by various age groups. This research aims to determine the content of kasturi oil, its formulation as a roll-on aromatherapy preparation, and its physical evaluation. \nMethods: The essential oil of kasturi orange peel was extracted using the distillation method, and then the physicochemical properties were examined. The chemical content of the oil was analyzed using GC-MS. The roll-on aromatherapy preparation formulas were made by varying concentrations of kasturi oil, F0 (0%), F1 (4%), F2 (6%), and F3 (10%). Additional substances used were menthol, camphor, patchouli oil, and virgin coconut oil. Patchouli oil was used in this preparation to make the aroma last longer. Evaluation of roll-on aromatherapy preparations includes organoleptic tests, pH tests, specific gravity, viscosity, clarity, and stability. \nResults: From the extraction results, the percentage yield of essential kasturi oil was 0.55% v/w, with a density of 0.85 g/ml and a refractive index of 1.469. From the chromatogram results, there were 18 compounds in kasturi oil; the largest component was D-limonene (32.59%). Physical evaluation results of all roll-on aromatherapy formulas had met the requirements. \nConclusion: From the chromatogram results, there were 18 compounds in kasturi oil, with the largest component were D-limonene (32.59%). Formula F3 had the best aroma intensity, approximately for 5 h, with a slightly strong aroma, and physical evaluation results of all roll-on aromatherapy formulas had met the requirements.","PeriodicalId":13737,"journal":{"name":"International Journal of Applied Pharmaceutics","volume":"12 10","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Applied Pharmaceutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22159/ijap.2024.v16s1.28","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
引用次数: 0

Abstract

Objective: Kasturi orange (Citrus microcarpa Bunge) is widely cultivated and consumed in Indonesia. The fruit's flesh is a good source of vitamin C. Essential oil of kasturi orange peel is one of the ingredients used as a raw material for aromatherapy roll-on preparations. Roll-on aromatherapy is currently widely used by various age groups. This research aims to determine the content of kasturi oil, its formulation as a roll-on aromatherapy preparation, and its physical evaluation. Methods: The essential oil of kasturi orange peel was extracted using the distillation method, and then the physicochemical properties were examined. The chemical content of the oil was analyzed using GC-MS. The roll-on aromatherapy preparation formulas were made by varying concentrations of kasturi oil, F0 (0%), F1 (4%), F2 (6%), and F3 (10%). Additional substances used were menthol, camphor, patchouli oil, and virgin coconut oil. Patchouli oil was used in this preparation to make the aroma last longer. Evaluation of roll-on aromatherapy preparations includes organoleptic tests, pH tests, specific gravity, viscosity, clarity, and stability. Results: From the extraction results, the percentage yield of essential kasturi oil was 0.55% v/w, with a density of 0.85 g/ml and a refractive index of 1.469. From the chromatogram results, there were 18 compounds in kasturi oil; the largest component was D-limonene (32.59%). Physical evaluation results of all roll-on aromatherapy formulas had met the requirements. Conclusion: From the chromatogram results, there were 18 compounds in kasturi oil, with the largest component were D-limonene (32.59%). Formula F3 had the best aroma intensity, approximately for 5 h, with a slightly strong aroma, and physical evaluation results of all roll-on aromatherapy formulas had met the requirements.
卡斯图里橙皮(Citrus microcarpa bunge)精油:化学成分、作为滚珠香薰的配方及其评估
目的卡斯图里橙(Citrus microcarpa Bunge)在印度尼西亚被广泛种植和食用。果肉是维生素 C 的良好来源。卡斯图里橙皮精油是香薰卷剂的原料之一。目前,各年龄段的人都在广泛使用滚珠香薰疗法。本研究旨在确定 kasturi 油的含量、其作为滚珠香薰疗法制剂的配方及其物理评估。研究方法采用蒸馏法提取卡斯图里橙皮精油,然后检测其理化性质。使用气相色谱-质谱分析了精油的化学成分。根据不同浓度的卡斯图瑞精油(F0(0%)、F1(4%)、F2(6%)和 F3(10%))配制出滚动式芳香疗法配方。另外还使用了薄荷醇、樟脑、广藿香油和初榨椰子油。使用广藿香油是为了让香气更持久。对滚珠香薰制剂的评估包括感官测试、pH 值测试、比重、粘度、透明度和稳定性。结果从萃取结果来看,卡斯图瑞精油的产量百分比为 0.55%(体积分数),密度为 0.85 克/毫升,折射率为 1.469。色谱结果显示,kasturi 油中含有 18 种化合物,其中最大的成分是 D-柠檬烯(32.59%)。所有滚珠香薰配方的物理评估结果均符合要求。结论从色谱结果来看,卡斯特里油中含有 18 种化合物,其中最大的成分是 D-柠檬烯(32.59%)。配方 F3 的香气强度最好,大约持续 5 小时,香气略浓,所有滚珠香薰配方的物理评估结果均符合要求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
International Journal of Applied Pharmaceutics
International Journal of Applied Pharmaceutics Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
CiteScore
1.40
自引率
0.00%
发文量
219
期刊介绍: International Journal of Applied Pharmaceutics (Int J App Pharm) is a peer-reviewed, bimonthly (onward March 2017) open access journal devoted to the excellence and research in the pure pharmaceutics. This Journal publishes original research work that contributes significantly to further the scientific knowledge in conventional dosage forms, formulation development and characterization, controlled and novel drug delivery, biopharmaceutics, pharmacokinetics, molecular drug design, polymer-based drug delivery, nanotechnology, nanocarrier based drug delivery, novel routes and modes of delivery; responsive delivery systems, prodrug design, development and characterization of the targeted drug delivery systems, ligand carrier interactions etc. However, the other areas which are related to the pharmaceutics are also entertained includes physical pharmacy and API (active pharmaceutical ingredients) analysis. The Journal publishes original research work either as a Original Article or as a Short Communication. Review Articles on a current topic in the said fields are also considered for publication in the Journal.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信