{"title":"Tuning Catalytic Attributes of Enzymes by Conjugation with Functionalized Carbon Dots","authors":"","doi":"10.1007/s11244-024-01911-1","DOIUrl":null,"url":null,"abstract":"<h3>Abstract</h3> <p>Enzymes are essential biological catalysts that can accelerate multiple reactions. Their outstanding catalytic properties make them highly valuable in different research fields and industries including pharmaceutical, sensing, food, and agriculture. However, the catalytic attributes of free enzymes are limited by their poor stability and resistance to harsh conditions. Recently, the conjugation of different enzymes with carbon dots (CDs) has been explored as a novel strategy for tuning their catalytic properties. CDs possess unique and tunable characteristics such as light stability, electron transfer properties, lower toxicity, cost-efficiency, and outstanding biocompatibility; thus, they represent excellent options for the conjugation of different enzymes to improve their stability, selectivity, and catalytic efficiency. Recently, various CDs-based nano-biocatalysts have been successfully prepared with superior performances compared to their free enzymes. Therefore, this review aims to discuss the most recent reported studies in the synthesis of CDs-based nano-biocatalysts providing an overview of current methodologies and recent research applications. Lastly, we delve into the prospects and the future possibilities of such innovative conjugates that entail an exploration of the faced challenges and their untapped potential for various applications.</p> <span> <h3>Graphical Abstract</h3> <p> <span> <span> <img alt=\"\" src=\"https://static-content.springer.com/image/MediaObjects/11244_2024_1911_Figa_HTML.png\"/> </span> </span></p> </span>","PeriodicalId":801,"journal":{"name":"Topics in Catalysis","volume":null,"pages":null},"PeriodicalIF":2.8000,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Topics in Catalysis","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s11244-024-01911-1","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
Enzymes are essential biological catalysts that can accelerate multiple reactions. Their outstanding catalytic properties make them highly valuable in different research fields and industries including pharmaceutical, sensing, food, and agriculture. However, the catalytic attributes of free enzymes are limited by their poor stability and resistance to harsh conditions. Recently, the conjugation of different enzymes with carbon dots (CDs) has been explored as a novel strategy for tuning their catalytic properties. CDs possess unique and tunable characteristics such as light stability, electron transfer properties, lower toxicity, cost-efficiency, and outstanding biocompatibility; thus, they represent excellent options for the conjugation of different enzymes to improve their stability, selectivity, and catalytic efficiency. Recently, various CDs-based nano-biocatalysts have been successfully prepared with superior performances compared to their free enzymes. Therefore, this review aims to discuss the most recent reported studies in the synthesis of CDs-based nano-biocatalysts providing an overview of current methodologies and recent research applications. Lastly, we delve into the prospects and the future possibilities of such innovative conjugates that entail an exploration of the faced challenges and their untapped potential for various applications.
摘要 酶是一种重要的生物催化剂，可以加速多种反应。酶的卓越催化特性使其在制药、传感、食品和农业等不同研究领域和行业中具有极高的价值。然而，游离酶的催化特性因其稳定性差和对恶劣条件的耐受性而受到限制。最近，人们探索了将不同的酶与碳点（CD）共轭，作为调整其催化特性的一种新策略。碳点具有独特的可调特性，如光稳定性、电子传递特性、低毒性、成本效益和出色的生物相容性；因此，它们是缀合不同酶以提高其稳定性、选择性和催化效率的绝佳选择。最近，人们成功制备了各种基于 CD 的纳米生物催化剂，其性能优于游离酶。因此，本综述旨在讨论有关合成 CD 基纳米生物催化剂的最新研究报告，概述当前的方法和最新的研究应用。最后，我们将深入探讨此类创新型共轭物的前景和未来可能性，包括所面临的挑战及其在各种应用中尚未开发的潜力。 图表摘要
期刊介绍：
Topics in Catalysis publishes topical collections in all fields of catalysis which are composed only of invited articles from leading authors. The journal documents today’s emerging and critical trends in all branches of catalysis. Each themed issue is organized by renowned Guest Editors in collaboration with the Editors-in-Chief. Proposals for new topics are welcome and should be submitted directly to the Editors-in-Chief.
The publication of individual uninvited original research articles can be sent to our sister journal Catalysis Letters. This journal aims for rapid publication of high-impact original research articles in all fields of both applied and theoretical catalysis, including heterogeneous, homogeneous and biocatalysis.
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