Chemotherapy-induced microbiota exacerbates the toxicity of chemotherapy through the suppression of interleukin-10 from macrophages

IF 12.2 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Gut Microbes Pub Date : 2024-02-24 DOI:10.1080/19490976.2024.2319511

Zhen He, Hongyu Xie, Haoyang Xu, Jinjie Wu, Wanyi Zeng, Qilang He, Christian Jobin, Sanqing Jin, Ping Lan

引用次数: 0

Abstract

The gut microbiota has been shown to influence the efficacy and toxicity of chemotherapy, thereby affecting treatment outcomes. Understanding the mechanism by which microbiota affects chemotherapeu...

查看原文本刊更多论文

化疗诱导的微生物群通过抑制巨噬细胞的白细胞介素-10而加剧化疗的毒性

肠道微生物群已被证明会影响化疗的疗效和毒性，从而影响治疗效果。了解微生物群对化疗的影响机制可以帮助我们更好地了解化疗的疗效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Gut Microbes Medicine-Microbiology (medical)

CiteScore

18.20

自引率

3.30%

发文量

196

审稿时长

10 weeks

期刊介绍： The intestinal microbiota plays a crucial role in human physiology, influencing various aspects of health and disease such as nutrition, obesity, brain function, allergic responses, immunity, inflammatory bowel disease, irritable bowel syndrome, cancer development, cardiac disease, liver disease, and more. Gut Microbes serves as a platform for showcasing and discussing state-of-the-art research related to the microorganisms present in the intestine. The journal emphasizes mechanistic and cause-and-effect studies. Additionally, it has a counterpart, Gut Microbes Reports, which places a greater focus on emerging topics and comparative and incremental studies.