Understanding the Burden of Nonalcoholic Fatty Liver Disease: Time for Action

Q3 Medicine

Diabetes Spectrum Pub Date : 2024-02-01 DOI:10.2337/dsi23-0010

Z. Younossi, Linda Henry

引用次数: 2

Abstract

The prevalence of nonalcoholic fatty liver disease (NAFLD) in the United States is 38%, having increased by 50% within the past 3 decades. The estimated NAFLD prevalence among people with type 2 diabetes is 55–70%. The presence of type 2 diabetes is associated with a higher likelihood of progression of NAFLD to fibrosis development, liver transplant, and death. Cardiovascular disease is the main cause of mortality among people with NAFLD, and the risk of death is significantly higher in people with both NAFLD and type 2 diabetes. NAFLD carries high patient and economic burdens but low awareness among both the general public and health care providers. This article reviews the epidemiology of NAFLD and discusses the need for appropriate risk stratification, referral for specialty care, management of cardiometabolic risk factors, and treatment of the disease. The authors present a call to action to raise awareness of NAFLD and address its increasing burden in a systematic and efficient manner.

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了解非酒精性脂肪肝的负担：行动起来

在美国，非酒精性脂肪肝（NAFLD）的发病率为 38%，在过去 30 年中增加了 50%。据估计，非酒精性脂肪肝在 2 型糖尿病患者中的发病率为 55-70%。2型糖尿病患者的非酒精性脂肪肝更有可能发展为肝纤维化、肝移植和死亡。心血管疾病是导致非酒精性脂肪肝患者死亡的主要原因，同时患有非酒精性脂肪肝和2型糖尿病的患者死亡风险明显更高。非酒精性脂肪肝给患者和经济带来了沉重负担，但公众和医疗服务提供者对其认识不足。本文回顾了非酒精性脂肪肝的流行病学，讨论了适当的风险分层、专科转诊、心脏代谢风险因素管理和疾病治疗的必要性。作者呼吁采取行动，提高人们对非酒精性脂肪肝的认识，并以系统、高效的方式解决其日益沉重的负担。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetes Spectrum Medicine-Internal Medicine

CiteScore

2.70

自引率

0.00%

发文量

期刊介绍： The mission of Diabetes Spectrum: From Research to Practice is to assist health care professionals in the development of strategies to individualize treatment and diabetes self-management education for improved quality of life and diabetes control. These goals are achieved by presenting review as well as original, peer-reviewed articles on topics in clinical diabetes management, professional and patient education, nutrition, behavioral science and counseling, educational program development, and advocacy. In each issue, the FROM RESEARCH TO PRACTICE section explores, in depth, a diabetes care topic and provides practical application of current research findings.