Innovative and sustainable synthesis and structure of novel N-substituted hexahydroacridine derivatives

IF 1.9 4区化学 Q2 CHEMISTRY, ORGANIC

Journal of Physical Organic Chemistry Pub Date : 2024-02-14 DOI:10.1002/poc.4604

Nangagoundan Vinoth, Chinnasamy Kalaiarasi, Appaswami Lalitha

引用次数: 0

Abstract

An efficient and green synthesis of tetramethyl-10-(phenylamino)-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione derivatives has been achieved from various substituted aryl aldehydes, 5,5-dimethyl-3-(2-phenylhydrazinyl)cyclohex-2-enone and dimedone in aqueous ethanol medium. Environment-friendly reaction, excellent yields, operational simplicity and shorter reaction times are the significant features of the present protocol. All the synthesized compounds were characterized by various spectroscopic techniques and X-ray crystal diffraction studies.

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新型 N-取代六氢吖啶衍生物的创新和可持续合成及其结构

在乙醇水溶液介质中，以各种取代的芳基醛、5,5-二甲基-3-(2-苯肼基)环己-2-烯酮和二咪酮为原料，高效、绿色地合成了四甲基-10-(苯基氨基)-3,4,6,7,9,10-六氢吖啶-1,8(2H,5H)-二酮衍生物。本方案的显著特点是反应对环境友好、产率高、操作简单和反应时间短。所有合成化合物都通过各种光谱技术和 X 射线晶体衍射研究进行了表征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Physical Organic Chemistry 化学-物理化学

CiteScore

3.60

自引率

11.10%

发文量

161

审稿时长

2.3 months

期刊介绍： The Journal of Physical Organic Chemistry is the foremost international journal devoted to the relationship between molecular structure and chemical reactivity in organic systems. It publishes Research Articles, Reviews and Mini Reviews based on research striving to understand the principles governing chemical structures in relation to activity and transformation with physical and mathematical rigor, using results derived from experimental and computational methods. Physical Organic Chemistry is a central and fundamental field with multiple applications in fields such as molecular recognition, supramolecular chemistry, catalysis, photochemistry, biological and material sciences, nanotechnology and surface science.