Depression in patients with hematologic malignancies: The current landscape and future directions

IF 6.9 2区 医学 Q1 HEMATOLOGY
Thomas M. Kuczmarski , Lizabeth Roemer , Oreofe O. Odejide
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引用次数: 0

Abstract

Patients with hematologic malignancies experience high rates of depression. These patients are vulnerable to depression throughout the disease trajectory, from diagnosis to survivorship, and at the end of life. In addition to the distressing nature of depression, it has substantial downstream effects including poor quality of life, increased risk of treatment complications, and worse survival. Therefore, systematic screening for depression and integration of robust psychological interventions for affected patients is crucial. Although depression has been historically studied mostly in patients with solid malignancies, research focusing on patients with hematologic malignancies is growing. In this article, we describe what is known about depression in patients with hematologic malignancies, including its assessment, prevalence, risk factors, and implications. We also describe interventions to ameliorate depression in this population. Future research is needed to test effective and scalable interventions to reduce the burden of depression among patients with blood cancers.

血液系统恶性肿瘤患者的抑郁症:当前形势与未来方向
血液系统恶性肿瘤患者的抑郁症发病率很高。这些患者在整个疾病过程中,从诊断到存活,以及在生命的最后阶段,都很容易受到抑郁症的困扰。抑郁症除了令人痛苦之外,还会产生严重的下游影响,包括生活质量低下、治疗并发症风险增加以及生存状况恶化。因此,对受影响的患者进行系统的抑郁症筛查并采取有力的心理干预措施至关重要。尽管抑郁症的研究历来主要针对实体瘤恶性肿瘤患者,但针对血液系统恶性肿瘤患者的研究正在不断增加。在本文中,我们将介绍血液恶性肿瘤患者抑郁症的相关知识,包括其评估、患病率、风险因素和影响。我们还介绍了改善该人群抑郁状况的干预措施。未来的研究需要测试有效且可推广的干预措施,以减轻血液癌症患者的抑郁负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Blood Reviews
Blood Reviews 医学-血液学
CiteScore
13.80
自引率
1.40%
发文量
78
期刊介绍: Blood Reviews, a highly regarded international journal, serves as a vital information hub, offering comprehensive evaluations of clinical practices and research insights from esteemed experts. Specially commissioned, peer-reviewed articles authored by leading researchers and practitioners ensure extensive global coverage across all sub-specialties of hematology.
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