Immunohistochemical analysis of soft tissue sarcomas. Comparisons with electron microscopy.

Abstract

Soft tissue sarcomas are capable of causing diagnostic bewilderment for the surgical pathologist, because of their diversity of differentiation and overlapping histologic appearances. Immunohistochemical studies provide a means whereby this confusion can be resolved in many cases, and electron microscopy also may play a useful role in this process. This overview presents a summary of results of these 2 adjuvant modalities of pathologic analysis, as applied to the spectrum of malignant soft tissue neoplasms.