Theranostics revolution in prostate cancer: Basics, clinical applications, open issues and future perspectives

IF 11.3 1区化学 Q1 CHEMISTRY, PHYSICAL

ACS Catalysis Pub Date : 2024-02-11 DOI:10.1016/j.ctrv.2024.102698

Matteo Bauckneht , Chiara Ciccarese , Riccardo Laudicella , Claudia Mosillo , Francesca D'Amico , Annunziato Anghelone , Alessandro Strusi , Viria Beccia , Sergio Bracarda , Giuseppe Fornarini , Giampaolo Tortora , Roberto Iacovelli

引用次数: 0

Abstract

In the last years, theranostics has expanded the therapeutic options available for prostate cancer patients. In this review, we explore this dynamic field and its potential to revolutionize precision medicine for prostate cancer. We delve into the foundational principles, clinical applications, and emerging opportunities, emphasizing the potential synergy between radioligand therapy and other systemic treatments. Additionally, we address the ongoing challenges, including optimizing patient selection, assessing treatment responses, and determining the role of theranostics within the broader landscape of prostate cancer treatment.

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前列腺癌的血清疗法革命：基础知识、临床应用、未决问题和未来展望

在过去几年中，前列腺癌治疗技术为前列腺癌患者提供了更多的治疗选择。在这篇综述中，我们将探讨这一充满活力的领域及其彻底改变前列腺癌精准医疗的潜力。我们深入探讨了基础原理、临床应用和新兴机遇，强调了放射性配体疗法与其他系统治疗之间的潜在协同作用。此外，我们还探讨了当前面临的挑战，包括优化患者选择、评估治疗反应以及确定治疗仪在前列腺癌治疗大环境中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Catalysis CHEMISTRY, PHYSICAL-

CiteScore

20.80

自引率

6.20%

发文量

1253

审稿时长

1.5 months

期刊介绍： ACS Catalysis is an esteemed journal that publishes original research in the fields of heterogeneous catalysis, molecular catalysis, and biocatalysis. It offers broad coverage across diverse areas such as life sciences, organometallics and synthesis, photochemistry and electrochemistry, drug discovery and synthesis, materials science, environmental protection, polymer discovery and synthesis, and energy and fuels. The scope of the journal is to showcase innovative work in various aspects of catalysis. This includes new reactions and novel synthetic approaches utilizing known catalysts, the discovery or modification of new catalysts, elucidation of catalytic mechanisms through cutting-edge investigations, practical enhancements of existing processes, as well as conceptual advances in the field. Contributions to ACS Catalysis can encompass both experimental and theoretical research focused on catalytic molecules, macromolecules, and materials that exhibit catalytic turnover.