Sleep Disordered Breathing and Risk for ADHD: Review of Supportive Evidence and Proposed Underlying Mechanisms.

IF 2.7 3区医学 Q2 PSYCHIATRY

Journal of Attention Disorders Pub Date : 2024-03-01 Epub Date: 2024-02-14 DOI:10.1177/10870547241232313

Iliyan Ivanov, Ben Miraglia, Dana Prodanova, Jeffrey H Newcorn

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引用次数: 0

Abstract

Background: Accumulating evidence suggests that sleep disordered breathing (SDB) is under-recognized in youth and adults with ADHD. SDB may contribute to exacerbating pre-existing ADHD symptoms and may play a role in the development of cognitive deficits that may mimic ADHD symptoms.

Method: We conducted a focused review of publications on cross-prevalence, overlapping clinical and neurobiological characteristics and possible mechanisms linking SDB and ADHD.

Results: Exiting studies suggest that co-occurrence of SDB and ADHD is as high as 50%, with frequent overlap of clinical symptoms such as distractibility and inattention. Mechanisms linking these conditions may include hypoxia during sleep, sleep fragmentation and activation of inflammation, all of which may affect brain structure and physiology to produce disturbances in attention.

Conclusions: The relationship between SDB and ADHD symptoms appear well-supported and suggests that more research is needed to better optimize procedures for SDB assessment in youth being evaluated and/or treated for ADHD.

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睡眠呼吸紊乱与多动症风险：支持性证据和潜在机制综述》（Review of Supportive Evidence and Proposed Underlying Mechanisms）。

背景：越来越多的证据表明，睡眠呼吸紊乱（SDB）在患有多动症的青少年和成人中未得到充分认识。SDB可能会加重原有的ADHD症状，并可能在模仿ADHD症状的认知缺陷的发展过程中发挥作用：我们对有关SDB和ADHD的交叉患病率、重叠的临床和神经生物学特征以及可能的关联机制的出版物进行了重点审查：现有研究表明，SDB和ADHD的并发率高达50%，临床症状经常重叠，如注意力分散和注意力不集中。这些病症的关联机制可能包括睡眠期间缺氧、睡眠片段化和炎症激活，所有这些因素都可能影响大脑结构和生理，从而导致注意力障碍：SDB与ADHD症状之间的关系似乎得到了很好的证实，这表明需要进行更多的研究，以更好地优化对接受ADHD评估和/或治疗的青少年进行SDB评估的程序。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Attention Disorders PSYCHIATRY-

CiteScore

7.60

自引率

6.70%

发文量

审稿时长

6-12 weeks

期刊介绍： Journal of Attention Disorders (JAD) focuses on basic and applied science concerning attention and related functions in children, adolescents, and adults. JAD publishes articles on diagnosis, comorbidity, neuropsychological functioning, psychopharmacology, and psychosocial issues. The journal also addresses practice, policy, and theory, as well as review articles, commentaries, in-depth analyses, empirical research articles, and case presentations or program evaluations.