Thrombolysis for ischaemic stroke despite direct oral anticoagulation.

IF 2.6 1区医学

Journal of Investigative Medicine Pub Date : 2024-11-05 DOI:10.1136/svn-2023-002727

Jan C Purrucker, Thomas R Meinel, Duncan Wilson, Ying Xian, Teddy Y Wu, David J Seiffge

引用次数: 0

Abstract

Intravenous thrombolysis is not recommended in anticoagulated patients receiving direct oral anticoagulants (DOACs) and a recent intake within the last 48 hours in US and European guidelines. However, three observational studies now suggest safety of thrombolysis in patients with recent intake of DOACs, and thus support previous experimental data. In this perspective, the current evidence and practical consequences are discussed.

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在直接口服抗凝药的情况下溶栓治疗缺血性中风。

在美国和欧洲的指南中，不建议接受直接口服抗凝剂（DOACs）治疗的抗凝患者在最近 48 小时内进行静脉溶栓治疗。然而，目前有三项观察性研究表明，近期服用 DOACs 的患者进行溶栓治疗是安全的，从而支持了之前的实验数据。本文将讨论当前的证据和实际后果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Investigative Medicine MEDICINE, GENERAL & INTERNALMEDICINE, RESE-MEDICINE, RESEARCH & EXPERIMENTAL

自引率

0.00%

发文量

111

期刊介绍： Journal of Investigative Medicine (JIM) is the official publication of the American Federation for Medical Research. The journal is peer-reviewed and publishes high-quality original articles and reviews in the areas of basic, clinical, and translational medical research. JIM publishes on all topics and specialty areas that are critical to the conduct of the entire spectrum of biomedical research: from the translation of clinical observations at the bedside, to basic and animal research to clinical research and the implementation of innovative medical care.