Bridge to Weight Loss: A Case Series.

IF 3.1 3区 医学 Q2 ENGINEERING, BIOMEDICAL
ASAIO Journal Pub Date : 2024-10-01 Epub Date: 2024-02-12 DOI:10.1097/MAT.0000000000002162
Robert A Solomon, Dennis J Kerrigan, Steven J Keteyian, Jennifer A Cowger
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引用次数: 0

Abstract

Durable left ventricular assist devices (LVADs) are a well-established therapeutic option for patients with advanced heart failure. These devices are often used to "bridge" patients to an orthotopic heart transplantation (HT). Unfortunately, many patients on LVAD support with a body mass index (BMI) above a certain value are not eligible for HT due a lack of suitable donors and the association between obesity and poor outcomes after HT. This case series describes three individuals on LVAD support who were able to successfully lose enough weight to qualify to be listed for an HT. We highlight a systematic, multidisciplinary approach to implementing guideline-driven weight loss strategies, including some aggressive methods ( ie , meal replacements, weight loss medications, and bariatric surgery). In addition to describing the weight loss outcomes, we also discuss barriers and medical challenges during weight loss that are unique to this population.

减肥之桥:病例系列。
耐用的左心室辅助装置(LVAD)是晚期心力衰竭患者一种行之有效的治疗选择。这些设备通常被用于为患者进行正位心脏移植(HT)"搭桥"。遗憾的是,由于缺乏合适的供体以及肥胖与心脏移植术后不良预后之间的关联,许多接受 LVAD 支持且体重指数(BMI)超过一定值的患者不符合接受心脏移植术的条件。本系列病例描述了三位接受 LVAD 支持的患者,他们成功地减掉了足够的体重,从而获得了接受 HT 的资格。我们重点介绍了一种系统的、多学科的方法来实施指南驱动的减肥策略,包括一些激进的方法(即代餐、减肥药物和减肥手术)。除了介绍减肥结果,我们还讨论了减肥过程中的障碍和医疗挑战,这些都是这一人群所特有的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ASAIO Journal
ASAIO Journal 医学-工程:生物医学
CiteScore
6.60
自引率
7.10%
发文量
651
审稿时长
4-8 weeks
期刊介绍: ASAIO Journal is in the forefront of artificial organ research and development. On the cutting edge of innovative technology, it features peer-reviewed articles of the highest quality that describe research, development, the most recent advances in the design of artificial organ devices and findings from initial testing. Bimonthly, the ASAIO Journal features state-of-the-art investigations, laboratory and clinical trials, and discussions and opinions from experts around the world. The official publication of the American Society for Artificial Internal Organs.
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