The Role of Early Life Gut Mycobiome on Child Health

IF 8 1区医学 Q1 NUTRITION & DIETETICS

Advances in Nutrition Pub Date : 2024-02-03 DOI:10.1016/j.advnut.2024.100185

Kayleigh Amber Rodriguez , Manoj Gurung , Rachelanne Talatala , Jolene R Rearick , Meghan L Ruebel , Kimberly E Stephens , Laxmi Yeruva

引用次数: 0

Abstract

The human gut microbiota is composed of bacteria (microbiota or microbiome), fungi (mycobiome), viruses, and archaea, but most of the research is primarily focused on the bacterial component of this ecosystem. Besides bacteria, fungi have been shown to play a role in host health and physiologic functions. However, studies on mycobiota composition during infancy, the factors that might shape infant gut mycobiota, and implications to child health and development are limited. In this review, we discuss the factors likely shaping gut mycobiota, interkingdom interactions, and associations with child health outcomes and highlight the gaps in our current knowledge of this ecosystem.

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生命早期肠道霉菌生物群对儿童健康的作用

人体肠道微生物群由细菌（微生物群或微生物组）、真菌（真菌生物群）、病毒和古细菌组成，但大多数研究主要集中于这一生态系统中的细菌成分。除细菌外，真菌也被证明在宿主健康和生理功能中发挥作用。然而，有关婴儿期真菌生物群的组成、可能影响婴儿肠道真菌生物群的因素以及对儿童健康和发育的影响的研究还很有限。在这篇综述中，我们将讨论可能影响肠道霉菌生物群的因素、菌群间的相互作用、与儿童健康结果的关联，并强调我们目前对这一生态系统认识的不足之处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in Nutrition 医学-营养学

CiteScore

17.40

自引率

2.20%

发文量

117

审稿时长

56 days

期刊介绍： Advances in Nutrition (AN/Adv Nutr) publishes focused reviews on pivotal findings and recent research across all domains relevant to nutritional scientists and biomedical researchers. This encompasses nutrition-related research spanning biochemical, molecular, and genetic studies using experimental animal models, domestic animals, and human subjects. The journal also emphasizes clinical nutrition, epidemiology and public health, and nutrition education. Review articles concentrate on recent progress rather than broad historical developments. In addition to review articles, AN includes Perspectives, Letters to the Editor, and supplements. Supplement proposals require pre-approval by the editor before submission. The journal features reports and position papers from the American Society for Nutrition, summaries of major government and foundation reports, and Nutrient Information briefs providing crucial details about dietary requirements, food sources, deficiencies, and other essential nutrient information. All submissions with scientific content undergo peer review by the Editors or their designees prior to acceptance for publication.