Rotator cuff tears.

IF 76.9 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Asheesh Bedi, Julie Bishop, Jay Keener, Drew A Lansdown, Ofer Levy, Peter MacDonald, Nicola Maffulli, Joo Han Oh, Vani J Sabesan, Joaquin Sanchez-Sotelo, Riley J Williams, Brian T Feeley
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Abstract

Rotator cuff tears are the most common upper extremity condition seen by primary care and orthopaedic surgeons, with a spectrum ranging from tendinopathy to full-thickness tears with arthritic change. Some tears are traumatic, but most rotator cuff problems are degenerative. Not all tears are symptomatic and not all progress, and many patients in whom tears become more extensive do not experience symptom worsening. Hence, a standard algorithm for managing patients is challenging. The pathophysiology of rotator cuff tears is complex and encompasses an interplay between the tendon, bone and muscle. Rotator cuff tears begin as degenerative changes within the tendon, with matrix disorganization and inflammatory changes. Subsequently, tears progress to partial-thickness and then full-thickness tears. Muscle quality, as evidenced by the overall size of the muscle and intramuscular fatty infiltration, also influences symptoms, tear progression and the outcomes of surgery. Treatment depends primarily on symptoms, with non-operative management sufficient for most patients with rotator cuff problems. Modern arthroscopic repair techniques have improved recovery, but outcomes are still limited by a lack of understanding of how to improve tendon to bone healing in many patients.

Abstract Image

肩袖撕裂
肩袖撕裂是初级保健和矫形外科医生最常见的上肢疾病,其范围从肌腱病变到伴有关节炎变化的全厚撕裂不等。有些撕裂是创伤性的,但大多数肩袖问题是退行性的。并非所有的撕裂都会出现症状,也并非所有的撕裂都会发展,许多撕裂范围更广的患者并不会出现症状恶化。因此,制定治疗患者的标准算法具有挑战性。肩袖撕裂的病理生理学非常复杂,包括肌腱、骨骼和肌肉之间的相互作用。肩袖撕裂最初是肌腱内部的退行性变化,伴有基质紊乱和炎症变化。随后,撕裂发展为部分厚度撕裂,然后是全厚度撕裂。肌肉质量(表现为肌肉的整体大小和肌肉内脂肪浸润)也会影响症状、撕裂进展和手术效果。治疗主要取决于症状,非手术治疗足以治愈大多数肩袖问题患者。现代关节镜修复技术改善了患者的恢复情况,但由于对如何改善许多患者肌腱与骨骼的愈合缺乏了解,治疗效果仍受到限制。
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来源期刊
Nature Reviews Disease Primers
Nature Reviews Disease Primers Medicine-General Medicine
CiteScore
76.70
自引率
0.20%
发文量
75
期刊介绍: Nature Reviews Disease Primers, a part of the Nature Reviews journal portfolio, features sections on epidemiology, mechanisms, diagnosis, management, and patient quality of life. The editorial team commissions top researchers — comprising basic scientists and clinical researchers — to write the Primers, which are designed for use by early career researchers, medical students and principal investigators. Each Primer concludes with an Outlook section, highlighting future research directions. Covered medical specialties include Cardiology, Dermatology, Ear, Nose and Throat, Emergency Medicine, Endocrinology, Gastroenterology, Genetic Conditions, Gynaecology and Obstetrics, Hepatology, Haematology, Infectious Diseases, Maxillofacial and Oral Medicine, Nephrology, Neurology, Nutrition, Oncology, Ophthalmology, Orthopaedics, Psychiatry, Respiratory Medicine, Rheumatology, Sleep Medicine, and Urology.
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