Linear streaks associated with retinitis pigmentosa.

IF 1.4 4区医学 Q3 OPHTHALMOLOGY

European Journal of Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-02-08 DOI:10.1177/11206721241232450

Maurizio Battaglia Parodi, Alessandro Arrigo, Emanuela Aragona, Adelaide Pina, Francesco Bandello

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引用次数: 0

Abstract

Purpose: To describe a phenotypical manifestation characterized by the identification of peripheral linear streaks associated with retinitis pigmentosa (RP).

Methods: Study design is a prospective observational case series. All consecutive patients affected by RP underwent a complete ophthalmological examination. The diagnosis of peripheral linear streaks was based on the identification of curvilinear atrophic streaks in the periphery of the retina.

Results: Overall, six out of 140 patients (4.2%) were affected by peripheral linear streaks associated with RP. A single patient showed also punched out chorioretinal lesions at the posterior pole, with macular neovascularization development over the follow-up, treated with ranibizumab injections.

Conclusions: RP phenotypical manifestation characterized by peripheral linear streaks is infrequent and may provide additional evidence to support the contribution of inflammation in the pathogenesis of RP.

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与视网膜色素变性有关的线状条纹。

目的：描述一种与视网膜色素变性（RP）相关的表型表现，其特征是发现周边线状条纹：研究设计为前瞻性观察病例系列。所有连续的 RP 患者都接受了全面的眼科检查。外周线状条纹的诊断依据是视网膜外周出现的曲线状萎缩条纹：总的来说，140 名患者中有 6 名（4.2%）患有与视网膜退行性病变相关的周边线状条纹。一名患者的视网膜后极部还出现了打孔的脉络膜病变，随访期间黄斑新生血管也有所发展，该患者接受了雷尼珠单抗注射治疗：结论：以外周线性条纹为特征的 RP 表型表现并不常见，可为支持炎症在 RP 发病机制中的作用提供更多证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Ophthalmology 医学-眼科学

CiteScore

3.60

自引率

0.00%

发文量

372

审稿时长

3-8 weeks

期刊介绍： The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.