SMR transporters meet the challenge of metformin metabolites.

IF 3.3 2区医学 Q1 PHYSIOLOGY

Journal of General Physiology Pub Date : 2024-03-04 Epub Date: 2024-02-07 DOI:10.1085/jgp.202413549

Ben Short

引用次数: 0

Abstract

JGP study (Lucero et al. http://www.doi.org/10.1085/jgp.202313464) shows that members of the SMRGdx subtype can export the degradation products of metformin, helping bacteria adapt to high environmental levels of the commonly prescribed diabetes medication.

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SMR 转运体迎接二甲双胍代谢物的挑战。

JGP研究（Lucero等人，http://www.doi.org/10.1085/jgp.202313464）显示，SMRGdx亚型的成员可以输出二甲双胍的降解产物，帮助细菌适应环境中高浓度的糖尿病常用药。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of General Physiology 医学-生理学

CiteScore

6.00

自引率

10.50%

发文量

审稿时长

6-12 weeks

期刊介绍： General physiology is the study of biological mechanisms through analytical investigations, which decipher the molecular and cellular mechanisms underlying biological function at all levels of organization. The mission of Journal of General Physiology (JGP) is to publish mechanistic and quantitative molecular and cellular physiology of the highest quality, to provide a best-in-class author experience, and to nurture future generations of independent researchers. The major emphasis is on physiological problems at the cellular and molecular level.