Molecular Interactions Leading to the Advancement in the Techniques for COVID-19 Detection: A Review

IF 1.7 4区 农林科学 Q3 CHEMISTRY, ANALYTICAL
Mohammad Kashif, Swati Acharya, Adila Khalil
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引用次数: 0

Abstract

Since 2019 the world is in a combat with the highly contagious disease COVID-19 that is caused by the rapid transmission of SARS-CoV-2 virus (severe acute respiratory syndrome- coronavirus-2). Detection of this disease in an early stage helps to control its spread and management. To combat this epidemic with one-time effective medication improved quick analytical procedures must be developed and validated. The requirement of accurate and precise analytical methods for the diagnosis of the virus and antibodies in infected patients has been a matter of concern. The global impact of this virus has motivated scientists and researchers to investigate and develop various analytical diagnostic techniques. This review includes the study of standard methods which are reliable and accredited for the analytical recognition of the said virus. For early detection of SARS-CoV-2 RNA, RT-PCR is an accurate method among other methods and thus, considered as “gold standard” technique. Here, we outline the most extensively used analytical methods for diagnosing COVID-19, along with a brief description of each technique and its analytical aspects/perspective.
导致 COVID-19 检测技术进步的分子相互作用:综述
自 2019 年以来,全世界都在与由 SARS-CoV-2 病毒(严重急性呼吸系统综合征-冠状病毒-2)快速传播引起的高传染性疾病 COVID-19 作斗争。早期发现这种疾病有助于控制其传播和管理。为了使用一次性有效药物来抗击这一流行病,必须开发和验证改进的快速分析程序。为诊断病毒和受感染病人体内的抗体,需要准确和精确的分析方法,这一直是一个值得关注的问题。这种病毒对全球的影响促使科学家和研究人员研究和开发各种分析诊断技术。这篇综述包括对可靠的标准方法的研究,这些方法在分析识别上述病毒方面得到了认可。在早期检测 SARS-CoV-2 RNA 的方法中,RT-PCR 是一种准确的方法,因此被认为是 "金标准 "技术。在此,我们概述了诊断 COVID-19 最广泛使用的分析方法,并简要介绍了每种技术及其分析方面/角度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of AOAC International
Journal of AOAC International 医学-分析化学
CiteScore
3.10
自引率
12.50%
发文量
144
审稿时长
2.7 months
期刊介绍: The Journal of AOAC INTERNATIONAL publishes the latest in basic and applied research in analytical sciences related to foods, drugs, agriculture, the environment, and more. The Journal is the method researchers'' forum for exchanging information and keeping informed of new technology and techniques pertinent to regulatory agencies and regulated industries.
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