Prognostic Factors for Functional Recovery at 1-Year Following Fragility Hip Fractures.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-02-01 Epub Date: 2023-12-15 DOI:10.4055/cios23177

Nitchanant Kitcharanant, Pichitchai Atthakomol, Jiraporn Khorana, Phichayut Phinyo, Aasis Unnanuntana

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引用次数: 0

Abstract

Background: The main objective of treating fragility hip fractures is to maximize the patients' ability to return to their basic activities of daily living (ADL) levels. This study explored prognostic factors associated with the ability to recover pre-fracture ADL levels at 1 year after fragility hip fractures.

Methods: We retrospectively recruited patients admitted with fragility hip fractures between July 2016 and September 2018. Details of the following were extracted from electronic medical records: age, sex, body mass index; pre-fracture Charlson Comorbidity Index (CCI), Barthel index, and EuroQol-Visual Analog Scale (EQ-VAS) scores; pre-fracture ambulatory status; and fracture type and treatment. The primary endpoint was the ability to return to the pre-fracture ADL status at 1 year. Multivariable logistic regression analysis assessed the prognostic ability of predictors.

Results: Of 405 patients, 284 (70.1%) managed to return to their pre-fracture ADL status. Multivariable logistic regression analysis demonstrated that the predictor with the most apparent effect size was pre-fracture EQ-VAS scores ≥ 65 (multivariable odds ratio [mOR], 12.90; p = 0.03). Other influential predictors were CCI scores < 5 (mOR, 1.96; p = 0.01) and surgical treatment for the hip fracture.

Conclusions: Three prognostic factors can predict a hip fracture patient's ability to return to the pre-fracture ambulatory status at 1 year. They are the patient's CCI score, operative treatment for the hip fracture, and the pre-fracture EQ-VAS score. This information could be used to develop a clinical prediction model based on the prognostic factors.

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脆性髋部骨折后 1 年功能恢复的预后因素

背景：治疗髋部脆性骨折的主要目的是最大限度地提高患者恢复基本日常生活（ADL）水平的能力。本研究探讨了与脆性髋部骨折后 1 年恢复骨折前 ADL 水平能力相关的预后因素：我们回顾性招募了2016年7月至2018年9月期间入院的脆性髋部骨折患者。我们从电子病历中提取了以下详细信息：年龄、性别、体重指数；骨折前的夏尔森合并症指数（CCI）、巴特尔指数和欧洲量表-视觉模拟量表（EQ-VAS）评分；骨折前的活动状态；骨折类型和治疗方法。主要终点是一年后恢复到骨折前ADL状态的能力。多变量逻辑回归分析评估了预测因素的预后能力：在405名患者中，284人（70.1%）成功恢复到骨折前的ADL状态。多变量逻辑回归分析表明，效果最明显的预测因子是骨折前 EQ-VAS 评分≥ 65（多变量几率比 [mOR]，12.90；p = 0.03）。其他有影响的预测因素是CCI评分<5（mOR，1.96；p = 0.01）和髋部骨折的手术治疗：结论：有三个预后因素可以预测髋部骨折患者在 1 年后恢复到骨折前活动状态的能力。它们分别是患者的CCI评分、髋部骨折的手术治疗以及骨折前的EQ-VAS评分。这些信息可用于开发基于预后因素的临床预测模型。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.