Antioxidant, antimicrobial, and skin-whitening effects and quantitative analysis of phenolic compounds in Korean wild Chrysanthemum flowers via HPLC/UV
IF 2.4 3区 农林科学Q1 Agricultural and Biological Sciences
Jeong So, Hak-Dong Lee, Ji Hyun Kim, Sanghyun Lee, Jin Hee Lim
{"title":"Antioxidant, antimicrobial, and skin-whitening effects and quantitative analysis of phenolic compounds in Korean wild Chrysanthemum flowers via HPLC/UV","authors":"Jeong So, Hak-Dong Lee, Ji Hyun Kim, Sanghyun Lee, Jin Hee Lim","doi":"10.1007/s13580-023-00570-7","DOIUrl":null,"url":null,"abstract":"<p>To assess the potential of Korean wild <i>Chrysanthemum</i> flowers as cosmetic ingredients, this study evaluated the antioxidant, antimicrobial, and skin-whitening activities of extracts from <i>Chrysanthemum zawadskii</i> var. <i>latilobum</i>, <i>C. zawadskii</i> var. <i>lucidum</i>, <i>C. zawadskii</i> var. <i>yezoense</i>, and <i>C. makinoi</i>. Subsequently, HPLC analyses were conducted to characterize the phenolic compound contents of these extracts. The Korean wild <i>Chrysanthemum</i> flowers exhibited strong antioxidant properties, as evidenced by in vitro radical scavenging activity assays. They also exhibited skin-whitening activity by inhibiting melanin contents in α-melanocyte-stimulating hormone-induced B16F10 cells. Notably, <i>C. zawadskii</i> var. <i>lucidum</i> displayed higher antioxidant activity due to its elevated flavonoid content and potent radical scavenging activity compared to other wild <i>Chrysanthemum</i> flowers. Furthermore, <i>C. makinoi</i> exhibited strong in vitro tyrosinase inhibitory activity and reduced melanin contents in comparison to the other wild <i>Chrysanthemum</i> flowers. Our findings also confirmed the antimicrobial activity of the wild <i>Chrysanthemum</i> flower extracts against <i>Staphylococcus aureus, Pseudomonas aeruginosa,</i> and <i>Candida albicans</i>. Additionally, our HPLC analyses revealed that C. <i>zawadskii</i> var. <i>lucidum</i> had significantly higher contents of chlorogenic acid, linarin, 3,5-di-<i>O</i>-caffeoylquinic acid, and 4,5-di-<i>O</i>-caffeoylquinic acid. Therefore, Korean wild <i>Chrysanthemum</i> flowers hold promise as functional cosmetic ingredients due to their antioxidant, antimicrobial, and skin-whitening effects, as well as their elevated levels of phenolic compounds.</p>","PeriodicalId":13123,"journal":{"name":"Horticulture Environment and Biotechnology","volume":null,"pages":null},"PeriodicalIF":2.4000,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Horticulture Environment and Biotechnology","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1007/s13580-023-00570-7","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Agricultural and Biological Sciences","Score":null,"Total":0}
引用次数: 0
Abstract
To assess the potential of Korean wild Chrysanthemum flowers as cosmetic ingredients, this study evaluated the antioxidant, antimicrobial, and skin-whitening activities of extracts from Chrysanthemum zawadskii var. latilobum, C. zawadskii var. lucidum, C. zawadskii var. yezoense, and C. makinoi. Subsequently, HPLC analyses were conducted to characterize the phenolic compound contents of these extracts. The Korean wild Chrysanthemum flowers exhibited strong antioxidant properties, as evidenced by in vitro radical scavenging activity assays. They also exhibited skin-whitening activity by inhibiting melanin contents in α-melanocyte-stimulating hormone-induced B16F10 cells. Notably, C. zawadskii var. lucidum displayed higher antioxidant activity due to its elevated flavonoid content and potent radical scavenging activity compared to other wild Chrysanthemum flowers. Furthermore, C. makinoi exhibited strong in vitro tyrosinase inhibitory activity and reduced melanin contents in comparison to the other wild Chrysanthemum flowers. Our findings also confirmed the antimicrobial activity of the wild Chrysanthemum flower extracts against Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans. Additionally, our HPLC analyses revealed that C. zawadskii var. lucidum had significantly higher contents of chlorogenic acid, linarin, 3,5-di-O-caffeoylquinic acid, and 4,5-di-O-caffeoylquinic acid. Therefore, Korean wild Chrysanthemum flowers hold promise as functional cosmetic ingredients due to their antioxidant, antimicrobial, and skin-whitening effects, as well as their elevated levels of phenolic compounds.
期刊介绍:
Horticulture, Environment, and Biotechnology (HEB) is the official journal of the Korean Society for Horticultural Science, was launched in 1965 as the "Journal of Korean Society for Horticultural Science".
HEB is an international journal, published in English, bimonthly on the last day of even number months, and indexed in Biosys Preview, SCIE, and CABI.
The journal is devoted for the publication of original research papers and review articles related to vegetables, fruits, ornamental and herbal plants, and covers all aspects of physiology, molecular biology, biotechnology, protected cultivation, postharvest technology, and research in plants related to environment.